"Similarly, reproductive aging and women’s health are finally on the scene: several initiatives have recognized not only that reproductive cessation is the earliest aging phenotype, but also that menopause itself (which is about 15 years later than reproductive aging, so not interchangeable) can cause aging, and that mid-life health may ultimately determine future longevity. This, plus the acknowledgment that female animals are important to study in all aspects of biology, may lead to the end of ignoring 50% of the aging population’s needs."

https://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.3002132