"Here, we performed an extensive profiling of systemic myeloid cell populations and plasma soluble factors in NSCLC patients undergoing PD-L1/PD-1 blockade therapies, before and during treatment. Responder patients showed an elevated diversity of myeloid cell types, enriched in activated monocytic cells, and decreased granulocytic populations. Plasma FKN concentration correlated with myeloid cell diversity and response to PD-L1/PD-1 blockade."
Bocanegra et al @emboreports
#Immunology #immunotherapy

https://www.embopress.org/doi/full/10.15252/embr.202255884