'Tessier-Lavigne will be blamed for his vigorous and sometimes bombastic denials of scientific misconduct (here, here, and here), which while perhaps technically correct, don’t read well in light of a report that says his lab culture allowed repeated manipulation of research data. But there is another big issue here that is important for science—running a research laboratory is a full-time job and can’t be done effectively when the principal investigator is simultaneously fulfilling a challenging administrative role.'
https://www.science.org/content/blog-post/tessier-lavigne-matter-shows-why-running-lab-full-time-job