"Here, we show that key metabolic functions of human hepatocytes are controlled by non-parenchymal cells (NPCs) in their microenvironment. We developed mice bearing human hepatic tissue composed of human hepatocytes and NPCs, including human immune, endothelial, and stellate cells. "

https://www.cell.com/cell/fulltext/S0092-8674(23)00795-X?dgcid=raven_jbs_aip_email#%20