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'Here, our goal is to review distinct domains of Treg function in the host response to respiratory infection and subsequent lung injury and discuss open questions in the field that should be addressed as Treg-based therapeutics move into translation.'
#Immunology #tregs
https://www.jci.org/articles/view/170505
A long time ago, in a galaxy far far away an outbreak of pneumocystis in our Rag colony led Jocelyne, Shohei & me to show that Tregs protect the lung from immunepathology in the course of an anti pathogen response.
https://onlinelibrary.wiley.com/doi/full/10.1002/1521-4141%28200205%2932%3A5%3C1282%3A%3AAID-IMMU1282%3E3.0.CO%3B2-%23?sid=nlm%3Apubmed