'Now, of course, I’ll point out that we’ve never really looked for flu in cattle before, and it’s conceivable that there have been outbreaks in cattle before that we just missed. But the cattle thing is something new, and new is bad, because we don’t know much about it. It’s very difficult to make predictions when we have no knowledge base that we’re acting on.'
https://www.nejm.org/doi/full/10.1056/NEJMp2405795