'What's surprising is that these things don't go on to show the same toxicity to eukaryotic cells, and I have to say, I wouldn't have expected that, especially since the initial screens used eukaryotic DNA). But the degree of DNA-induced aggregation correlates quite well with the antibacterial activity (and for that matter, the degree of self-aggregation is a pretty good surrogate for the DNA-induced aggregation).'
https://www.science.org/content/blog-post/new-way-kill-bacteria