'How loss of the germline increases longevity in C. elegans has remained unknown. This study shows that germline ablation is sensed by adhesion disruption between germline stem cells (GSCs) and gonadal niche cells, altering stromal expression patterns and cytokine secretion for enhanced longevity signalling in distal tissues.'

https://www.embopress.org/doi/full/10.1038/s44318-024-00185-3