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"Male sex has long been recognized as a potent nonmodifiable risk factor for abdominal aortic aneurysms (AAA). AAA is approximately four to six times more prevalent in men than in women (7), but females experience faster rates of aneurysm growth, and their aneurysms tend to rupture at smaller sizes (...)
In this issue of the JCI, Mu and colleagues present compelling evidence that androgens exacerbate AA by suppressing programmed cell death protein 1 (PD-1) in mice"
#Immunology
