'In this work, we developed a mRNA–LNP vaccine targeting C. difficile toxins & virulence factors. This multivalent vaccine elicited robust and long-lived systemic & mucosal antigen-specific humoral and cellular immune responses across animal models, independent of changes to the intestinal microbiota.'
#Immunology

https://www.science.org/doi/10.1126/science.adn4955