@macroliter Of course they are
Age old debate. When inferior may not really be inferior.
In this case, does a negative urine after treatment really indicate a better clinical outcome? (personally, no)
#IDMastodon #MedMastodon #AMR #antibiotics #microbiology #urine #academia
Antimicrobial for 7 or 14 days for febrile urinary tract infection in men: a multicenter noninferiority double blind placebo-controlled, randomized clinical trial | Clinical Infectious Diseases
https://academic.oup.com/cid/advance-article-abstract/doi/10.1093/cid/ciad070/7035974
My latest Clinical Pipeline column for #NatureMedicine is out, a look at Moderna's RNA vaccine for RSV & a survey of what's, well, in the pipeline, for RSV immunotherapies, including vaccines and monoclonals.
#Vaccine #drugdiscovery #drugdevelopment #mRNA #RSV #immunology #MonoclonalAntibody
Print by Madalena Parreira & Constança Arouca
“Map 10 The Turbulence Chart (Lviv, Ukraine, circa 1890)
This engraving was part of a set that illustrated the fabled, never published, “Order & Disorder” manuscript by Bronislaw Zamoyski (sometimes referred to as the “Leibniz of Lviv”). The text and all accompanying illustrations were thought to have been lost when the Russian Army captured Lviv in 1914. How it was obtained by von Willebrand remains unknown.”
RT @SocDevBio
Congrats to Anne Ephrussi @embl on receiving the 2023 @Dev_Bio_Journal-SDB Lifetime Achievement Award for her fundamental contributions to our understanding of RNA localization and translational control during development. http://bit.ly/3xtAMjM
In the context of within-host (intrahost) virus evolution, what are the best one-word terms for describing those single nucleotide variants (iSNVs) that were present in the infecting genotype, versus those derived via de novo mutation during infection? #virus #evolution
Fascinating host-manipulation story in @PLOSBiology
"Here, we characterise a plasmid translational regulator, RsmQ, capable of taking global regulatory control in Pseudomonas fluorescens and causing a behavioural switch from motile to sessile lifestyle."
https://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.3001988
"Together, our data suggest a model in which the hypodermis, a metabolic tissue, can non-autonomously regulate neuronal activity and function, indicating a systemic connection between metabolism and memory regulation."
#neuroscience #Celegans
"Preprint
On this day in 1971: Francis Peyton Rous died, won 1966 Nobel Prize for discovering first virus to cause cancer #NobelPrize #ThisDayInBiotech
Oxytocin is more than just the “love hormone” triggering prosocial behaviours, according to new research, writes @FlavorScience—it also sharpens our perception of social cues: https://t.co/CRIKBvJbSt https://t.co/tqB4OsCUae
"It is estimated that six million people in the United States, and thirty-five million people worldwide, currently suffer from Alzheimer’s disease. That number is expected to rise significantly, with a new case of dementia occurring every minute, because, in the nearly hundred and twenty years since Alois #Alzheimer’s finding, no one has figured out how to slow the progression of the disease, let alone prevent it or reverse its damage."
https://www.newyorker.com/science/annals-of-medicine/the-promise-of-a-new-alzheimers-drug
Vienna’s Albertina Museum Puts 150,000 Digitized Artworks Into the Public Domain: Klimt, Munch, Dürer, and More
Journal editing is a lot more than implementing policies. To help get us on the same page, I created this guide for Collabra: Psychology editors. I thought others might be interested, too. It's full of (possibly wrong) opinions. I hope it stimulates discussion!
https://docs.google.com/presentation/d/1zzEItmrMQpA3stKTL2X4Sl1XFCq6Qbi1uTYEwHb6-zE/edit?usp=sharing
Love it or hate it? Please share & give feedback!
@PavelTomancak
and I have an idea that could radically change how science papers are written so we know exactly who thought of each idea, who ran each experiment, and who analyzed the data 🧐🔥👇
https://nature.com/articles/s41580-023-00587-x
@NatRevMCB
Here's a free access link:
https://rdcu.be/c5MHl
Happy to share our latest preprint by Daniel Oyanedel et al.
Cooperation and cheating orchestrate Vibrio assemblages and polymicrobial synergy in oysters infected with OsHV-1 virus
https://www.biorxiv.org/content/10.1101/2023.02.11.528104v1
See how a herpes virus and cytotoxic Vibrio synergize to kill oysters.
An #interview with Mayssa Mokalled
Reviews Editor @amjeve speaks to Mayssa Mokalled, recipient of the 2022 Rising Star Award from the International Society for Regenerative Biology, about she became interested in #devbio and tissue #regeneration
https://journals.biologists.com/dev/article/150/4/dev201628/287023/An-interview-with-Mayssa-Mokalled
Born in 1750, Caroline Herschel worked as assistant to her astronomer brother William. But she also made her own discoveries of nebulae, stars & 8(!) comets.
In 1787, King George III officially employed Caroline as her brother's assistant, including a small salary that made her the first woman paid for her contribution to #science.
Caroline submitted over 550 stars to the existing star catalog & received honorary membership in the Royal Society. https://www.space.com/17439-caroline-herschel.html #history #HistoryRemix
I've worked on all of science, from B cells to T cells.
https://fellowsherpa.com