I'm very glad to see this paper out! @Phylogenetrips has done amazing work on detecting positive selection taking into account population variation in a phylogenetic framework. #phylogenomics #MolecularEvolution #NaturalSelection https://biologists.social/@biorxiv_evobio/111169917451799911
Spatial single-cell mass spectrometry defines zonation of the hepatocyte proteome - Nature Methods https://www.nature.com/articles/s41592-023-02007-6
What you see in this image are the blood vessels of the brain in a one-day old zebrafish. To visualize data such as these, scientists use transgenic reporter lines that light up the blood vessels with specific fluorophores and state-of-the-art light-sheet microscopes.
#microscopy #microscopyart #scienceart #scienceartist #scienceartwork #sciart #sciartist #scienceandart #sciencecommunication #ScienceComm #scicomm #scicom #microscopy #microscopyart #imageanalysis #imageprocessing #dataanalysis
"The three texts were sent on April 4, 2022. In the nearly 18 months since then, many of the decisions #Musk made after he bought Twitter appear to have closely followed that #RoadMap, up to and including his ongoing attacks against the ADL..."
Scientist/Lead Researcher/Senior Researcher
St. Jude Children's Research Hospital
See the full job description on jobRxiv: https://jobrxiv.org/job/scientist-lead-researcher-senior-researcher/?feed_id=60534
“The trouble is that we have a bad habit, encouraged by pedants and sophisticates, of considering happiness as something rather stupid. Only pain is intellectual, only evil interesting. This is the treason of the artist: a refusal to admit the banality of evil and the terrible boredom of pain.” — Ursula K. Le Guin
Microbe Talk: Conversations on Collaboration: Hilary Lappin-Scott on cultivating international partnerships | Microbiology Society https://microbiologysociety.org/blog/microbe-talk-conversations-on-collaboration-hilary-lappin-scott-on-cultivating-international-partnerships.html
⚠ Meta will apparently to move to a "Pay for your Rights" model in the European Union!
EU users would then have to pay $ 168 a year if they don't want to give up their fundamental right to privacy on Facebook and Instagram. This move is inacceptable.
"The aesthetic potential of scientific #data"
"Notably, infection and transmission of SARS-CoV-2 in mink resulted in adaptive mutations in the virus genome, and viruses with these mink-origin mutations were detected in humans, suggesting mink-to-human transmission of the virus"
#SarsCov2 #Covid19 #Covid #HostPathogen
PrEP prevents HIV infections, but it's not reaching Black women
A significant number of new HIV infections happen among Black women, and a health education effort in Atlanta wants to make sure Black women can access the HIV-prevention medicines known as PrEP. #press
"Back at the turn of the 21st century, valley fever was an obscure fungal disease in the United States, with fewer than 3,000 reported cases a year, mostly in California and Arizona. Two decades later, cases of valley fever have exploded, increasing roughly sevenfold by 2019."
"Suella Braverman’s latest assertionthat multiculturalism has “failed” proved that when it comes to immigration, we have moved away from dog whistles and back towards the sort of Powellite language that, even decades ago, was considered beyond the pale."
More about this endeavour and our expertise in knowledge representation and #environmental #bioinformatics: https://www.sib.swiss/news/unlocking-the-potential-of-microbes-to-make-plants-climate-resilient @dessimoz
Twitter/X "will collect information about the location of users and their private messages, which may constitute mass surveillance."
@NicoleCRust STAT had an interesting op piece on this last year https://www.statnews.com/2022/02/01/kariko-problem-lessons-funding-basic-research/
How do we support the Katalin Karikó's?
There's a lot of reasonable outrage today around how Katalin Karikó was treated throughout her career (full disclosure: by my employer, UPenn). Obviously a number of someones made a huge mistake by not recognizing the brilliance and potential of her work - no question there!
What I've been thinking about and I'd love to get some scenius input on: how could we, as an academic community, do better?
Here's one summary of what happened:
Taking seriously the notion that 1) we want to support the Katalin Karikó's but 2) high-risk, high-reward research takes time, here are a few ideas:
*) Better support to help geniuses communicate (and fund) their ideas.
*) More funding for high-risk, high-reward projects
*) A longer evaluation period for individuals engaged in high-risk/high-reward research
What would you add/change?
"Scholars and publishers have our own unique areas of expertise, responsibilities, and experiences of the manifold crises into which higher education is perpetually forced. But at base, scholars’ working conditions are publishers’ working conditions. If we want to change these conditions, we have to begin by recognizing—and working together to find—our common ground. Manufactured austerity; corporatization; competition over supposedly scarce resources; attrition and downsizing; mass PhD production; adjunctification; shrinking enrollments; escalating expectations to publish or perish; and, of course, the ongoing devastation of the COVID-19 pandemic and the right’s war against academic freedom: these issues affect us all."
I've worked on all of science, from B cells to T cells.
QOTO: Question Others to Teach Ourselves
An inclusive, Academic Freedom, instance
All cultures welcome.
Hate speech and harassment strictly forbidden.