Thiago Carvalho @cyrilpedia@qoto.org
I've worked on all of science, from B cells to T cells.
https://fellowsherpa.com
Joined Nov 2022
Thiago Carvalho
boosted
@girlscientist and I wrote this piece on issues and options around clinical genetics and genomics and social media: https://onlinelibrary.wiley.com/doi/full/10.1002/ajmg.a.63166
"Here, we report that a high sugar diet reduces Drosophila female fertility by increasing death of early germline cysts (prior to follicle formation) and degeneration of vitellogenic follicles; that obesity in and of itself does not impair fertility; and that high glucose levels closely correlate with reduced fertility on a high sugar diet."
Thiago Carvalho
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This ⬇️ looks really interesting! Need to read it carefully (just screened it), but I immediately thought about the potential impact/implications (?) within the glyco-RNA discovery #glycotime #preprints @raflynn
"RNA scaffolds the Golgi ribbon by forming condensates with GM130"
https://qoto.org/@biorxivpreprint/109959358348917080
"In November 2021, Compass published its initial results from the study on people with treatment-resistant depression. A single dose of psilocybin, combined with therapy, was shown to have a significant effect in the short term, improving depression scores for 37 per cent of patients three weeks after the trial, with 29 per cent in remission."
https://www.ft.com/content/e8dbeaea-9b65-41ae-a86a-07e9c4058456
The plot, as they say, thickens:
'Rishi Sunak is refusing to rush Britain back into the EU’s €95.5bn Horizon science programme despite his recent breakthrough in relations with Brussels, raising the prospect of a tough negotiation on rejoining the scheme.'
https://www.ft.com/content/409bccc7-8cb4-4f44-87c4-340d15147c55?sharetype=blocked
Thiago Carvalho
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Our latest Issue is now complete! Check out the full Table of contents here: https://journals.biologists.com/jcs/issue/136/4
#cellbiology #research #science #sciencemastodon
“I simply wanted to recover the heritage – the ancient traditions and vines – left to us by our ancestors,” said Torres, the president of Familia Torres winery. “And then we realised that some of these varieties take longer to ripen, meaning they might be able to help us in a warming world.”
Thiago Carvalho
boosted
Excited to present our work on measuring reproducibility of self-organized stem-cell assemblies in collab with @gregorscience at the #DevStem conference @ISTAustria today!
Many awesome talks and posters across the field lined up for this yearly Vienna conference!
'We have reached the point where scientists are warning not only that we are facing a mass extinction event, but that one is already under way. Can history — and not only human history — help us frame a response to the climate concerns of the modern age?'
https://www.ft.com/content/33e66ae3-dac2-4cc0-b859-79edc7dd07dd
Thiago Carvalho
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RT @mrillig
Are you a female researcher with an interest in ecological synthesis, meta-analysis, quantitative methods, machine learning?
Please get in touch!
Making one appointment of a 2-year postdoc fellowship this year through the @AvHStiftung Henriette-Herz Program
Thiago Carvalho
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A throwback piece on the Instituto Gulbenkian de Ciencia page about a small workshop that Miguel Soares & I organised on resistance and tolerance in 2010. This was back when most immunologists hearing "tolerance" would think only of T and B cell selection (and the occasional regulatory T cells). I'm a big fan of the small workshop, where everyone discusses unpublished work and feels free to speculate. We need more of these meetings.
https://gulbenkian.pt/ciencia/news/scientists-retreat-gave-away-new-era-fight-against-infections/
Thiago Carvalho
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Eight storytelling tips from one of my favorite writers. Here's #1:
"Use the time of a total stranger in such a way that he or she will not feel the time was wasted."
#KurtVonnegut
https://www.themarginalian.org/2012/04/03/kurt-vonnegut-on-writing-stories/
Thiago Carvalho
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A milestone for a young field:
Our community recommendations for single-cell proteomics are published OA in Nature Methods
Thiago Carvalho
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RT @medical_xpress
'Semantic similarity' leads to novel #drugcandidates for #Parkinson'sdisease @PLOS @PLOSBiology https://doi.org/grvqh4 https://medicalxpress.com/news/2023-03-semantic-similarity-drug-candidates-parkinson.html
Thiago Carvalho
boosted
Preclinical study of anti-IL8 in endometriosis:
"We created a long-acting recycling antibody against IL-8 (AMY109) and evaluated its clinical potency. Because rodents do not produce IL-8 and do not experience menstruation, we analyzed the lesions in cynomolgus monkeys that spontaneously developed endometriosis and in a surgically induced endometriosis monkey model."
#Immunology #monoclonalantibodies #Endometriosis #inflammation
Thiago Carvalho
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With a beautiful view of the Canals
'Yet it is still early days for AI drug discovery. There are a lot of AI companies making claims they can’t back up, says Prakash: “If somebody tells you they can perfectly predict which drug molecule can get through the gut or not get broken up by the liver, things like that, they probably also have land to sell you on Mars.”
Thiago Carvalho
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Haruki Murakami on originality in art & literature (from "Novelist as a Vocation".
#books #writers #bookshelf #literature
Thiago Carvalho
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Postdoctoral position in ecology, evolution, and genetics of Dictyostelium discoideum and its bacteria
The Queller-Strassmann group at Washington University in St. Louis has a postdoctoral position for a highly motivated individual interested in exploring this fascinating microbial system. We will begin reviewing applications by March 20 and will continue to accept them until the positions are filled. Start date is flexible.
I've worked on all of science, from B cells to T cells.
https://fellowsherpa.com
Joined Nov 2022
