Thiago Carvalho @cyrilpedia@qoto.org
I've worked on all of science, from B cells to T cells.
https://fellowsherpa.com
Joined Nov 2022
Thiago Carvalho
boosted
RT @Virus_Immunity
Antibody-mediated protection against symptomatic COVID-19 can be achieved at low serum neutralizing titers https://www.science.org/doi/10.1126/scitranslmed.adg2783#.ZBwRG5i8eZk.twitter
Thiago Carvalho
boosted
I found this article really helpful, and it is great to remember the positive things we can bring to our jobs
https://direct.mit.edu/jocn/article/35/1/44/113591/10-Simple-Rules-for-a-Supportive-Lab-Environment
Thiago Carvalho
boosted
How is #biomass production controlled during cell growth and the cell cycle?
New assay by Clovis Basier & Paul Nurse @thecrick using unperturbed exponentially growing populations shows how #cellcycle and cell size affect global rates of RNA and protein synthesis in #fissionyeast
#RefereedPreprint c/o @ReviewCommons now published in revised form!
Thiago Carvalho
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#FGF modulates cell adhesion to help salivary glands branch out
A Research Highlight showcasing new work from Ayan Ray & Philippe Soriano
Read the full Research Article, 'FGF signaling regulates #SalivaryGland branching morphogenesis by modulating cell adhesion' here:
A reviewer said, "This linkage between FGF signalling and #CellAdhesion provides a useful new dimension to understanding the mechanisms of #FGFsignalling".
Thiago Carvalho
boosted
In their #OpenAccess Review, Marlieke Jongsma, Nina Bakker & Jacques Neefjes describe the endosomal dance, and its coordination by molecular motors, which transports lipids, proteins and nutrients in the cell.
Thiago Carvalho
boosted
Enquanto há quem nos queira convencer de que o que leva os jovens a emigar são os impostos sobre os escalões mais altos de rendimento, quem estuda a sério o fenómeno no Observatório da Emigração percebe que o problema está mesmo nos salários baixos pagos pelas empresas.
🐦🔗: https://n.respublicae.eu/joseggusmao/status/1638856571127222273
"Structure includes prominent treatment of the famous duck-rabbit Gestalt switch in which you can see only one of the animals at a time, implying that each represented a different constellation of beliefs or perceptual frame. Kuhn had allowed a metaphorical aid to be taken literally, and later admitted that it had been a ‘dreadful mistake’. He respected the philosophers and was appalled to find that so many of them accused him of being a relativist, an irrationalist or a truth-denier – he was, he said, ‘much fonder of my critics than my fans’."
https://www.lrb.co.uk/the-paper/v45/n07/steven-shapin/paradigms-gone-wild
Thiago Carvalho
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A general ‘code’ which is independent of cell type controls how molecules of RNA are shuttled to their final destination. https://elifesciences.org/digests/80040/the-rules-of-traffic?utm_source=mastodon&utm_medium=social&utm_campaign=organic
"The continued misuse of Ivermectin reminds us that a dangerous idea doesn’t go away when it’s removed from the center of attention on major social-media platforms. In fact, as some researchers have argued, it may become more concentrated—a greater source of identity and of in-group self-definition."
Thiago Carvalho
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Unexpected #endosymbiont complexity in a fly species, wherein a #Wolbachia bacterium that kills males lives alongside a second strain that causes #CytoplasmicIncompatibility in the same host @MosWhisperer @drosobachia @PEARG_Lab &co #PLOSBiology https://plos.io/3TEicQe
Thiago Carvalho
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WE ARE HIRING!
We are looking for a postdoctoral fellow to work on an @ERC_Research@respublicae.funded grant.
https://erc.europa.eu/projects-statistics/stories/why-people-share-disinformation
The candidates should have
- PhD degree in #computerscience, #mathematics, #physics
- experience in #complexsystems, #networks, or #socialnetworkanalysis.
We are an equally opportunity employer and encourage applications from underrepresented groups
For more details:
https://www.euraxess.pt/jobs/85833
Please boost!
When editors write.
"I pouted for two weeks before I finally went back to work, pulling the editorial letter out of the drawer, careful not to strain a muscle under the sheer weight. Upon closer inspection, it was a truly excellent note."
https://lithub.com/if-doctors-make-the-worst-patients-do-editors-make-the-worst-authors/
Thiago Carvalho
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Ben Barres was a trailblazing transgender neurobiologist who promoted equity & diversity.
His pioneering research on glial cells changed science & he became the 1st #trans person admitted into the National Academies of Science.
Barres was also a strong advocate for women, early career scientists & the #LGBTQ+ community at a time when few people openly discussed gender identity.
Excerpt from his autobiography: https://stanmed.stanford.edu/ben-barres-autobiography-transgender-scientist/ #history #HistoryRemix
Thiago Carvalho
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For Robert Aldrich, unforgettably, she was Milly in #AutumnLeaves (1956) and Blanche in #WhatEverHappenedToBabyJane? (1962). To the world, she was the legendary, Oscar-winning #JoanCrawford
(1906-77), born in San Antonio #OnThisDay.
#BornOnThisDay #BOTD #OTD #GoldenEraHollywood #FilmNoir #HagHorror
2/2
Alternative lifestyles
"Turns out, B. compniacensis spores are widespread but the fungus does not outgrow its microbial neighbors unless there's ethanol in the air. It's been long known that some 2% of the ethanol in distilled spirits evaporates yearly during aging in barrels, this portion generally referred to as the Angel's Share. Not surprisingly, B. compniacensis is generally called the Angel's Share fungus: it has the striking ability to grow on ethanol vapors."
https://schaechter.asmblog.org/schaechter/2023/03/a-whiff-of-taxonomy-baudoinia-compniacensis.html
@achterbrain A great way for future AIs to remember and commemorate humans :)
Thiago Carvalho
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Many museums 🏛 are focused on (histories of) human artifacts 🏺🗿.
As intelligent artificial agents become influential in society, will we see these museums also documenting the evolving cognition of artificial agents?
Papers like this lay the groundwork:
https://arxiv.org/abs/2303.12712
Immune suppression with steroids is of course a part of the classical clinical armamentarium - two things are interesting here on this (mouse) cytokine release syndrome (CRS) paper: at the basic level, it explores an analogous physiologic regulatory circuit; in terms of clinical potential, it shows good effects (in mice) of low dose pretreatment - a viable option for CRS, as it is often caused by a clinical intervention.
"Mice treated with CD3 antibodies were protected against lethal CRS by the production of glucocorticoids (GC) induced by the adrenal stress response in a manner dependent on the scavenger receptor B1 (SR-BI), a receptor for high-density lipoprotein (HDL). Mice with whole-body or adrenal gland-specific SR-BI deficiency exhibited impaired GC production, more severe CRS, and increased mortality in response to CD3 antibodies."
Thiago Carvalho
boosted
A Whiff of Taxonomy – Baudoinia compniacensis
by Roberto
Several of our past posts described volatile organic compounds of microbial origin that influence our behavior. Acetates from wine, geosmin from soil. Not only are they enjoyable in the moment, such scents often elicit memories. I now offer the opposite perspective...
Read more → https://schaechter.asmblog.org/schaechter/2023/03/a-whiff-of-taxonomy-baudoinia-compniacensis.html
@ct_bergstrom There's a good piece in the FT today about the level of private control over the development of these tools. It shows not just a concentration, but how the scale of investment and proprietary nature of the tech put it largely beyond researchers & regulators ability to investigate the dangers and biases.
"A lack of access means researchers cannot replicate the models built in corporate labs, and can therefore neither probe nor audit them for potential harms and biases very easily."
https://www.ft.com/content/e9ebfb8d-428d-4802-8b27-a69314c421ce
I've worked on all of science, from B cells to T cells.
https://fellowsherpa.com
Joined Nov 2022
