Thiago Carvalho @cyrilpedia@qoto.org

New article! Read Enhancing breadth and durability of humoral immune responses in non-human primates with an adjuvanted group 1 influenza hemagglutinin stem antigen https://www.nature.com/articles/s41541-023-00772-1?utm_source=dlvr.it&utm_medium=mastodon in npj Vaccines

😢😢😢 but also the water companies got away with too much for too long https://www.theguardian.com/environment/2023/nov/11/photographer-project-wildlife-lost-pollution-yorkshire-river-wharfe?CMP=Share_iOSApp_Other

Group B streptococci adapt to survive in inflammation of diabetic wounds
#IDMastodon #infectiousdiseases #diabetes #microbiology #bacteria
https://www.science.org/doi/10.1126/sciadv.add3221

Tools

"Here we present a new optogenetic CRISPR tool, BLU-VIPR, that diverges from prevailing split-Cas design strategies and instead focuses on optogenetic regulation of gRNA production."

#Crispr #Optogenetics #Preprint

https://www.biorxiv.org/content/10.1101/2023.11.09.566272v1

"Ultimately, however, Factor VIII killed many of those who infused it in the 1970s and 1980s. For decades, British officials and ministers claimed that the contaminated blood scandal was a tragedy no one could have prevented: when haemophiliacs began to be infected, hepatitis C hadn’t even been named, and HIV/Aids was entirely unknown; new protocols were introduced once the dangers became clear. According to Margaret Thatcher, ‘all patients received the best treatment available in light of the medical knowledge at the time.’ These claims were not true."

https://www.lrb.co.uk/the-paper/v45/n22/florence-sutcliffe-braithwaite/we-ve-messed-up-boys

Just a few months after the launch of ChatGPT, copywriters and graphic designers (freelancers) have been affected by a significant drop in the number of contracts received, and in those that have received them - a drop in earnings. being more skilled was no shield against loss of work or earnings. Being more skilled was no shield against loss of work or earnings
https://papers.ssrn.com/sol3/papers.cfm?abstract_id=4527336 #ai #aftificialintelligence #chatgpt #gpt

https://www.bmj.com/content/370/bmj.m3379

The updated WHO recommendations for Covid treatment

“In sum, there is no denying that women’s path to leadership positions is paved with many barriers including a very thick glass ceiling. But a much bigger problem is the lack of career obstacles for incompetent men [..] The result is a pathological system that rewards men for their incompetence while punishing women for their competence, to everybody’s detriment.”
https://hbr.org/2013/08/why-do-so-many-incompetent-men

#Gaza Patients and medical staff trapped in hospitals under fire - ATTACKS MUST STOP NOW!

My colleagues recently published a paper on #apoptosis in the #drosophila dorsal #epidermis. They have shown that two factors can predict #cell #extrusion and apoptosis. Cell size sensed by #hippo and relative cell size (compared to neighbors) sensed by #notch

https://www.cell.com/current-biology/fulltext/S0960-9822(23)01298-8

Did you know that ErrantScience has an impact factor of 3 top hats, we hope one day to get it up to 6 imaginary frogs

Weekend #Plankton #Factoid 🦐🦠
A bit of a strange one. Rotifers can increase #microplastics particles by their feeding mechanism. #Rotifers feed by a ciliated corona, which looks like a wheel spinning (thus "wheeled animacules") into a pharynx with calcified trophi. When plastic particles are eaten, they are broken up into smaller bits. Rotifers are very common in #freshwater where most microplastics are deposited, potentially making the situation worse. #zooplankton
https://www.theguardian.com/environment/2023/nov/09/microplastic-eating-plankton-worsening-crisis-oceans-plastic-pollution