Thiago Carvalho @cyrilpedia@qoto.org
I've worked on all of science, from B cells to T cells.
https://fellowsherpa.com
Joined Nov 2022
Thiago Carvalho
boosted
As expected, Starmer's born-again Hard Brexiter stance (no EU, no single market, no customs union) is falling apart even before Labour's elected. It's like he's promising to cure a disease without using any medicine. Making Brexit work by homeopathy.
Within a year or two, he & Reeves will have to backtrack in the face of economic reality or look like fools when their do-nothing approach fails to cure any of the crippling problems caused by their own Hard Brexit policy.
Thiago Carvalho
boosted
Wasn’t it May last year when the government took away masks in healthcare?
I suppose that was so nobody would notice they opened up a lab full of animals infected with viruses in Kansas.
It’s absolutely wild to me that the one of the red states that screamed about how they have a right to spread Covid because it was a lab leak or a bio weapon are now fine with a potential leaky lab in their state.
'Há, no entanto, em especial, um grupo que escapou à penalização do seu papel na ditadura: os juízes dos Tribunais Plenários. Esses juízes eram serventuários da PIDE, exactamente serventuários, impediam qualquer simulacro de julgamento e de lei'
https://www.publico.pt/2024/06/22/opiniao/opiniao/justos-avancam-ofensiva-politica-impuros-2094868
'The book is also something of a diptych. The resonances between the two greatest public-health crises of Fauci’s tenure at niaid are impossible to ignore. Both cases involve asymptomatic infection, a scramble for tests and treatments, public-information campaigns, and the search for a vaccine—miraculously fast for covid-19, still unfulfilled for H.I.V. '
https://www.newyorker.com/magazine/2024/06/24/on-call-a-doctors-journey-in-public-service-anthony-fauci-book-review
Thiago Carvalho
boosted
Radioactive drugs strike cancer with precision
https://arstechnica.com/science/2024/06/radioactive-drugs-strike-cancer-with-precision/ #medicine #cancer #treatment #drugs #radiopharmaceuticals
Thiago Carvalho
boosted
It took five years to write, but here's the full story behind Lambda School, Silicon Valley's disastrous foray into for-profit education.
I explain how they burned through $120 million in funding, why Income Share Agreements failed, the crimes committed along the way, and how one developer turned journalist put an end to the fraud.
Thiago Carvalho
boosted
New blood test detects ovarian cancer years before conventional methods
https://www.livescience.com/health/cancer/new-blood-test-detects-ovarian-cancer-years-before-conventional-methods #medicine #diagnosis #OvarianCancer #detection #HGOC #biomarkers
'Patients with liver metastases derive limited benefit from immunotherapy independent of other established biomarkers of response. In multiple mouse models, we show that liver metastases siphon activated CD8+ T cells from systemic circulation. Within the liver, activated antigen-specific Fas+CD8+ T cells undergo apoptosis following their interaction with FasL+CD11b+F4/80+ monocyte-derived macrophages.'
#Immunology
https://www.nature.com/articles/s41591-020-1131-x
Thiago Carvalho
boosted
Rethinking Earth’s Timeline: New Research Reveals That Fresh Water Emerged 500 Million Years Sooner Than Previously Thought
https://scitechdaily.com/rethinking-earths-timeline-new-research-reveals-that-fresh-water-emerged-500-million-years-sooner-than-previously-thought/ #geology #EarthHistory #Fres
Tasty, but often lacking in nutritional value:
"First, there is Causal Salad: You put everything into a regression equation, toss with some creative story-telling, and hope the reviewers eat it. In general, this is not a valid approach, for well-known reasons. But it can get you published. Causal salad can discover causes too. But you have to get lucky. The Salad isn’t only regression. Really any procedure that hopes to take a list of variables (features) and return causal inference is Causal Salad. No amount of data reliably turns salad into sense."
https://elevanth.org/blog/2021/06/15/regression-fire-and-dangerous-things-1-3/
Thiago Carvalho
boosted
Parents: Kids are more depressed these days, i wonder why?
Kids: You destroyed the economy for us, the earth is literally dying, we are going to work until we die and on top of that the Nazis are back.
Parents: It's those pesky Necco Wafers
Thiago Carvalho
boosted
As I keep having to emphasize: Farage is a fascist and a Quisling. (And Putin is also a fascist, the one pulling Farage's strings.)
https://mastodon.online/@Geri/112656130818703600
'We find that diapause evolved by a recent remodeling of regulatory elements at very ancient gene duplicates (paralogs) present in all vertebrates. CRISPR-Cas9-based perturbations identify the transcription factors REST/NRSF and FOXOs as critical for the diapause gene expression program, including genes involved in lipid metabolism.'
Thiago Carvalho
boosted
#Starmer’s growth plan ‘doomed’ without access to EU markets, warn economists - https://www.theguardian.com/uk-news/article/2024/jun/22/starmer-growth-plan-doomed-access-eu-markets-economists "Labour leader told if elected he will have to rejoin the customs union to meet party’s manifesto pledges, while 56% of voters say #Brexit was bad for economy"
Thiago Carvalho
boosted
Did you know you can view our UKRIO webinars on our YouTube page?
Speakers from UKRIO and invited experts will explore topics such as Publication Ethics and Authorship; Research Data; Implementation of the Concordat to Support Research Integrity; Research Ethics; Consent in Research; and Research Integrity training.
View here https://zurl.co/KamM
#Speakers #Research #Training #Implementation #GuestSpeakers #YouTube
'De pouquíssimos intelectuais públicos se pode dizer que estão em condições de comemorar em vida os 85 anos do seu primeiro artigo político. Mas é o caso de Chomsky: foi em 1939, tinha ele dez anos, que publicou um primeiro artigo político no jornal da sua escola, em Filadélfia, sobre a Guerra Civil de Espanha.'
@ruitavares
https://expresso.pt/opiniao/2024-06-20-a-semana-em-que-chomsky-nao-morreu-2f332ce5
Thiago Carvalho
boosted
Why is #immunotherapy so difficult in patients with #liver #metastases. In this systematic analyses, Weiping Zou and colleagues try to unravel the #immunology at work in their manuscript.
https://www.nature.com/articles/s41591-020-1131-x
"Among the 247,854 COVID-19-related papers published in PubMed, 12,152 were initially released as preprints and were eventually published in 1,380 journals. This number is more than five times the 246 journals to which submissions can be made directly from bioRxiv through the B2J program. Journals with higher impact factors and Normalized Eigenfactor scores tend to publish a larger number of preprint-derived articles"
https://www.biorxiv.org/content/10.1101/2024.05.28.596359v1
Thiago Carvalho
boosted
Conformational modulation of a mobile loop controls catalysis in the (βα)8-barrel enzyme of histidine biosynthesis HisF https://www.biorxiv.org/content/10.1101/2024.06.21.600150v1?med=mas
Thiago Carvalho
boosted
‘How to Write Better Dialogue (While Becoming a Better Person)’
Let's discuss what you can learn from interviewing others - both to enrich your writing and your life.
#writing #writingtips #writinglife #writingcommunity #screenwriting #lifelessons
https://colehaddon.substack.com/p/how-to-master-writing-dialogue-while
I've worked on all of science, from B cells to T cells.
https://fellowsherpa.com
Joined Nov 2022
