Thiago Carvalho @cyrilpedia@qoto.org
I've worked on all of science, from B cells to T cells.
https://fellowsherpa.com
Joined Nov 2022
On Piezo as an RNA sensor in the gut:
"This is an important study that resolves a controversy about a proposed molecular linkage between the fields of mechanobiology and RNA signaling. While prior research had claimed that a specific mechanosensitive ion channel in the gut responds to a specific fecal RNA, this study provides compelling evidence that the mechanosensitive ion channel does not respond to the RNA."
Thiago Carvalho
boosted
When does mRNA level not predict protein level? A new paper from our lab revisited the question of how well mRNA levels reflect protein variances across different tumors and normal tissues using CPTAC data.
https://journals.plos.org/ploscompbiol/article?id=10.1371/journal.pcbi.1010702
Thiago Carvalho
boosted
New postdoc position to join my group at the Sars Centre, in #SunnyBergen https://www.jobbnorge.no/en/available-jobs/job/236193/postdoctoral-research-fellow-position-developmental-systems-in-a-simple-marine-chordate
Thiago Carvalho
boosted
RT @campathpostdocs@twitter.com
We're looking for postdocs to help with teaching supervisions (small group teaching) on many topics in the UoC Department of Pathology - if you're a University of Cambridge or UoC associated postdoc (any dept) and you might be interested, please DM me!
🐦🔗: https://twitter.com/campathpostdocs/status/1587384675420577793
Thiago Carvalho
boosted
New posting! A riff on the dream of community-led feedback on research findings, the #ReproducibilityCrisis, the problem of policing data integrity, and one possible alternative - that we all make an effort to praise and highlight good-quality work when we encounter it. Hope you like it.
https://totalinternalreflectionblog.com/2022/11/27/praise-censure-and-the-dream-of-open-science/
Thiago Carvalho
boosted
The Brooklyn Public Library Gives Every Teenager in the U.S. Free Access to Books Getting Censored by American Schools
Thiago Carvalho
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We're new here, so it's probably #introduction time! 👋
This is the official #Mastodon account of the @EU_Commission European Research Executive Agency.
We manage #HorizonEU, #MSCA, #RFCS, and #EUAgriPromo projects.
Follow us for #EU research and innovation news, including #funding opportunities and the latest updates from projects.
Join us and get involved in building a greener and more inclusive #Europe!
Thiago Carvalho
boosted
RT @lydiaemman
In Sunday @nytimes paper today⬇️📰by me & @LaurenMarkham_
Contributions from Greek journalists & orgs doing impressive work in difficult conditions @e_triantafillou @insidestory_gr @Chondrogiannos @reporters_gr @Malichudis @we_are_solomon @StefLoukopoulos @vouliwatch and... https://twitter.com/nytimes/status/1596563193970802690
Thiago Carvalho
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"People survive by passing information between themselves...We’re putting that fundamental quality through a process with an inherent incentive for corruption and degradation" https://www.theguardian.com/technology/2022/nov/27/jaron-lanier-tech-threat-humanity-twitter-social-media
Thiago Carvalho
boosted
We're hiring a senior editor at Scientific American to help run our opinion, commentary & analysis coverage. Thanks for applying or recommending the job to people you think would be good candidates. https://careers.springernature.com/job/New-York-Senior-Opinion-Editor%2C-Scientific-American/866115301/
Thiago Carvalho
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RT @LabListon@twitter.com
For anyone doing #flowcytometry, would you like to have a new protocol that reduces your #antibody costs by ~10-fold and also gives you higher quality data, with better signal-to-noise ratio?
Yes? Then read work by @olivertburton@twitter.com and @CarlyEWhyte@twitter.com. 1/6
https://currentprotocols.onlinelibrary.wiley.com/doi/epdf/10.1002/cpz1.589
🐦🔗: https://twitter.com/LabListon/status/1592270393578065921
Thiago Carvalho
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Nothing in biology makes sense except in the light of RNA sequencing, but what if you can't analyze the data? We (mostly Guy) created a software to make your life easy! Read our NEW preprint & REBLOG. Please try it (follow the detailed tutorial) and give us feedback! 🤟🙏
"RNAlysis: analyze your RNA sequencing data without writing a single line of code"
https://www.biorxiv.org/content/10.1101/2022.11.25.517851v1
Here's Guy's thread with all the details:
https://twitter.com/GuyTeichman/status/1596193414885810180?s=20&t=25MH4VPG-6PcqObk04bjVA
Thiago Carvalho
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RT @NobelPrize@twitter.com
What is life? This is a question that has puzzled scientists for centuries, including Nobel Prize laureates Erwin Schrödinger and Paul Nurse.
Nurse will be discussing this question in depth at this year's Nobel Week Dialogue. Register here: https://bit.ly/3s5Ttr4 https://t.co/JRhwCk6fiS
🐦🔗: https://twitter.com/NobelPrize/status/1596824678429065217
Thiago Carvalho
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So I hope the study is interesting and useful! In some ways, it is a negative results paper. But we believe it contributes an important set of observations for the field. We find AMPs do not intrinsically affect lifespan in flies.
We also show how a cryptic viral infection can greatly impact how we might have interpreted our results (fig incl), and reflect on the many challenges we were conscious of as we prepared our final manuscript.
Thiago Carvalho
boosted
https://www.biorxiv.org/content/10.1101/2022.08.24.504952v2
Our study on intrinsic effects of AMPs to healthy aging has now been reviewed by Review Commons! You can find the reviews via TRiP and our response letter (✅ in tabs on bioRxiv). Reviewers commented on a lack of sex-specific effect discussion, which I think makes for a great thread topic 🧵:
“Your scientists were so preoccupied with whether or not they could, they didn't stop to think if they should.”
'My argument was that it’s a really bad scientific strategy to just invent some mathematics, then proclaim we have to go and test it when there’s no reason it should work. There are infinitely many of those particles you can make up, and it’s not working. Just look at what’s come out of it in the past 40 years.'
'Here, we used genetically diverse C. elegans strains to perform dose-response analyses across 26 anthelmintic drugs that represent the three major anthelmintic drug classes (benzimidazoles, macrocyclic lactones, and nicotinic acetylcholine receptor agonists) in addition to seven other anthelmintic classes.'
I've worked on all of science, from B cells to T cells.
https://fellowsherpa.com
Joined Nov 2022
