Thiago Carvalho @cyrilpedia@qoto.org

An interesting look at the research and research management culture at Bell Labs (via The Browser).

"Over the years, Bell Labs management developed a small but coherent set of constraints and rules of thumb to ensure that its researchers internalized that, as Jim Fisk put it, it was “a matter of individual responsibility” to choose the right problems and that Bell Lab’s success in doing this at scale, across thousands of individuals, was “essentially automatic.”"

https://freaktakes.substack.com/p/how-did-places-like-bell-labs-know?ref=thebrowser.com

"The FDA is letting the industry know that it’s interested in streamlining the accelerated approval process for new cancer drugs, but that they’re not interested in making it too easy, either. They’re open to the idea of a “one-trial” route to such approvals, but it had better be a good trial."

https://www.science.org/content/blog-post/tightening-accelerated-approval

Country road (with cork)

'As cancer formation, growth, and progression subvert and repurpose mechanisms of development and regeneration, the nervous system may be implicated in all aspects of cancer pathophysiology. Reciprocally, cancer and cancer therapies can influence and remodel the nervous system, contributing to pathological feedback loops that not only yield neurological dysfunction but can also drive malignancy.'

https://www.cell.com/cell/fulltext/S0092-8674(23)00104-6

'Sagan, físico y astrofísico, exploraba el universo con su carisma, efectos visuales rústicos (punteros para la época), dramatizaciones de época y la bella música de Vangelis. Daba respuestas claras y hacía buenas preguntas.'

https://elpais.com/television/2023-04-28/cosmos-carl-sagan-tenia-razon-y-le-hicimos-poco-caso.html#?rel=lom

'The Cures Act went into full effect in the spring of 2021, granting patients access to their records by default, so that they didn’t have to request it. In the brief lull between covid-19’s soul-crushing winter and the start of the deadly Delta wave, the medical profession abruptly found itself staring into a two-way mirror.'

https://www.newyorker.com/news/essay/the-curious-side-effects-of-medical-transparency

'El Gobierno de extrema derecha de Giorgia Meloni ha planteado sus políticas en materia de migrantes bajo la enseña de la inhumanidad. Empezando por la vergüenza del estado de emergencia, que permitirá a la presidenta del Gobierno italiano emitir órdenes ministeriales sin debatirlas en el Consejo de Ministros y mucho menos en el Parlamento'

https://elpais.com/ideas/2023-04-23/la-crueldad-en-el-vertice-de-europa-meloni-migrantes-y-politica.html

'The founders of Melbourne’s Steam Room program believe scientists can make their work more accessible through humour. Will their hypothesis prove true?'

https://www.theguardian.com/science/2023/apr/30/the-science-of-standup-can-you-train-someone-to-be-funny

'At the beginning of a week that has seen April temperatures in Spain soar 7C to 11C above seasonal averages, the government reminded people to stay hydrated and make regular checks on vulnerable people such as babies, children and older people.'

https://www.theguardian.com/world/2023/apr/30/the-suit-burns-madrids-street-performers-suffer-in-record-spanish-heat

'Scientists have long known that dense breast tissue is linked to an increased risk of breast cancer in women. A study published on Thursday in JAMA Oncology adds a new twist, finding that while breast density declines with age, a slower rate of decline in one breast often precedes a cancer diagnosis in that breast.'

https://www.nytimes.com/2023/04/28/health/breast-cancer-density.html?action=click&module=Well&pgtype=Homepage&section=Health

'Ventura e Pacheco Amorim não são imaturos nem imberbes. A restante bancada do partido desperta adjetivos, mas não é nenhum destes. Os grupos económicos, as famílias e as personalidades, que apoiam e financiam o Chega, também não são gaiatos a fazer traquinices e representam, sim, motivações e interesses muito antigos, cuja aurora remonta ao Estado Novo. Infantil é o vice-presidente do PSD quando se convence de que as suas palavras convencem e de que, com esta leveza, nos atira areia para os olhos.'

https://www.publico.pt/2023/04/28/opiniao/opiniao/nao-sao-nada-racistas-sao-marotos-2047695

'The bloc is negotiating an amended deal with Pfizer despite the European public prosecutor opening a criminal investigation into their original agreement'

https://www.ft.com/content/fbcd28ad-f39a-4eae-8ffd-1baf940f41f1