Thiago Carvalho @cyrilpedia@qoto.org
I've worked on all of science, from B cells to T cells.
https://fellowsherpa.com
Joined Nov 2022
“It’s stunning,” says the immunologist Barney Graham, the former deputy director of the Vaccine Research Center and a central figure in the development of mRNA vaccines, who has lately been writing about a “new era for vaccinology.” “You cannot imagine what you’re going to see over the next 30 years. The pace of advancement is in an exponential phase right now.”
https://www.nytimes.com/2023/06/23/magazine/golden-age-medicine-biomedical-innovation.html
Thiago Carvalho
boosted
Engineer with PhD in embedded systems
Elvesys - Elveflow
Do you have a #PhD and have skills in #EmbeddedSystems? Come join us in #Paris to build together the future of #microfluidics!
See the full job description on jobRxiv: https://jobrxiv.org/job/elvesys-elveflow-27778-engineer-with-phd-in-embedded-systems/?feed_id=48467
#ScienceJobs #hiring #research #EngineeringJobs @elveflow #PhDjobs ...
https://jobrxiv.org/job/elvesys-elveflow-27778-engineer-with-phd-in-embedded-systems/?feed_id=48467
Thiago Carvalho
boosted
Controlling for false discoveries subsequently to large scale one‐way ANOVA testing in proteomics: Practical considerations | https://analyticalsciencejournals.onlinelibrary.wiley.com/doi/10.1002/pmic.202200406?af=R #proteomics
Thiago Carvalho
boosted
"Scientists warn that even a slight 0.8C (1.5F) increase in global #ocean temperatures represents “an enormous amount of #heat, large enough to transform marine #biodiversity, change ocean chemistry, raise #SeaLevels and fuel #ExtremeWeather”. "
Thiago Carvalho
boosted
Once someone makes the underlying assumptions explicit, you know what's coming next. Buckle up, tissue resident cell fate mapping, it's going to be a bumpy ride:
"Fate-mapping studies using conditional reporter genes and regulated expression of cre recombinase have led to the view that most resident tissue macrophage populations are established during embryonic development and maintained in the adult by self-renewal with minimal input from bone marrow progenitors or blood monocytes. The interpretation of fate-mapping studies depends upon multiple assumptions: (i) that expression of cre recombinase has no effect on monocyte-macrophage homeostasis, (ii) that tamoxifen is a neutral agonist, (iii) that life in an SPF animal facility reflects the normal life course of a mouse, and (iv) that the C57Bl/6J inbred mouse is a generalizable model and the biology of the MPS is unaffected by mouse genetic background or species."
Thiago Carvalho
boosted
Thiago Carvalho
boosted
'To address this critical knowledge gap, we conducted a comprehensive cross-species analysis of transcriptomic data from over 6000 blood samples from macaques and humans infected with one of 31 viruses, including #Lassa, #Ebola, #Marburg, #Zika, and #dengue.'
#Immunology #Virology #preprint
https://www.biorxiv.org/content/10.1101/2023.06.22.546003v1?med=mas
Thiago Carvalho
boosted
"King of censorship" is a good way of describing Musk
https://gizmodo.com/10-times-elon-musk-censored-twitter-users-1850570720
Thiago Carvalho
boosted
New video of Arthropod Antics finding "golden ants" in Costa Rica.
Once someone makes the underlying assumptions explicit, you know what's coming next. Buckle up, tissue resident cell fate mapping, it's going to be a bumpy ride:
"Fate-mapping studies using conditional reporter genes and regulated expression of cre recombinase have led to the view that most resident tissue macrophage populations are established during embryonic development and maintained in the adult by self-renewal with minimal input from bone marrow progenitors or blood monocytes. The interpretation of fate-mapping studies depends upon multiple assumptions: (i) that expression of cre recombinase has no effect on monocyte-macrophage homeostasis, (ii) that tamoxifen is a neutral agonist, (iii) that life in an SPF animal facility reflects the normal life course of a mouse, and (iv) that the C57Bl/6J inbred mouse is a generalizable model and the biology of the MPS is unaffected by mouse genetic background or species."
Thiago Carvalho
boosted
A great week at the soon to be extinct Gulbenkian Science Institute/IGC teaching MD PhD students of the EMERALD program.
Thiago Carvalho
boosted
Britain’s shorter children reveal a grim story about austerity, but its scars run far deeper | Michael Marmot https://www.theguardian.com/commentisfree/2023/jun/25/britains-shorter-children-reveal-a-grim-story-about-austerity-but-its-scars-run-far-deeper
Thiago Carvalho
boosted
Civilization dies when the only answer to "why can he do that?" is "because you can't stop him."
Thiago Carvalho
boosted
On this day in 1991: Michael Heidelberger died aged 103, key pioneer of immunochemistry #ThisDayInBiotech
Thiago Carvalho
boosted
More about Macchiarini https://www.bmj.com/content/381/bmj.p1367
Thiago Carvalho
boosted
George and the FT might be hearing from The Onion's legal team soon.
https://www.ft.com/content/05808970-09a0-4f86-af23-4f05db627742
Thiago Carvalho
boosted
'Nos últimos 17 anos, Portugal enviou 309,6 milhões de euros para Universidade Carnegie Mellon, o Instituto de Tecnologia do Massachusetts (MIT) e a Universidade do Texas em Austin, contou António Sousa Pereira, explicando que as transferências se inserem numa parceria lançada entre 2006 e 2007, através da Fundação para a Ciência e a Tecnologia (FCT).'
'The clinic is not just a place where Gaustine treats patients; it is also the perfect conceit for Gospodinov’s narrator to explore the 20th century in Europe through the vanishing points of traumatised or broken individuals. It’s as if Oliver Sacks and WG Sebald had collaborated on a Europe-wide chain of treatment centres.'
Thiago Carvalho
boosted
Communicating science through art: engaging conversation at the @Ecsite conference last week, with ERC grantee @kostas_nikolop of @unibirmingham.
Read more about his #sciart #scicomm activities 👉 https://erc.europa.eu/projects-figures/stories/dancing-particles https://t.co/9vojhS836f
🐦🔗: https://n.respublicae.eu/ERC_Research/status/1672590448031039489
I've worked on all of science, from B cells to T cells.
https://fellowsherpa.com
Joined Nov 2022
