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USG at last is putting serious resources into new Covid vaccine research. But there's a lot of confusion and uncertainty as it gets underway. Ben Mueller, Noah Weiland, and I report here: nytimes.com/2023/06/26/health/

A delegação portuguesa à COP-28 tem a obrigação de aproveitar esta oportunidade histórica e defender uma melhor colaboração e cooperação internacional neste domínio. O acesso a recursos e conhecimento deve ser partilhado. As dinâmicas de poder e as desigualdades históricas que os condicionam devem ser desmanteladas. Estamos juntos no mesmo planeta e a saúde é um bem universal a que todos têm direito

👇👀👇

onovo.pt/opiniao/momento-de-vi

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Celebrating 25 years of the International Brain Bee!
The 2023 IBB World Championship will be held virtually from July 31 to August 5, in conjunction with the #AmericanPsychologicalAssociation convention in Washington, DC. National Brain Bee champions from around the world will come together for an exciting competition and educational social program. www.thebrainbee.org

"Even if this turns out not to be widespread, it’s a good reminder: Malaria could make a comeback in the US, and we — and our public health infrastructure — ought to be prepared. This is especially true as a changing climate and shifting weather patterns increasingly drive mosquito migration into new places worldwide, allowing malaria to settle in where it hasn’t before." #entomology #insects #mosquitoes #malaria #VectorBorneDisease vox.com/science/2023/6/23/2377

#^Ola ka honua


Meet the forest that a community brought back to life on the slopes of a volcano in a hopeful story of ecological restoration
- by Aeon Video

Watch at Aeon

The trial is for idiopathic pulmonary fibrosis.

'The company said the drug, INS018_055, was the first entirely “AI-discovered and AI designed” drug to begin a phase 2 clinical trial and represented an important milestone for the industry.'

ft.com/content/82071cf2-f0da-4

“Proper planning, adequate resourcing and swift action saves lives. From the families’ perspectives, the UK had none of those three things.” I’m sympathetic to these views, but here’s a question: who was well prepared, not with hindsight but before the pandemic?'

ft.com/content/14324ba2-ae25-4

'Germline hemizygous loss-of-function mutations affecting the actin regulator DOCK11 were shown to cause a previously unknown inborn error of hematopoiesis and immunity characterized by severe immune dysregulation and systemic inflammation, recurrent infections, and anemia.'

nejm.org/doi/full/10.1056/NEJM

'The clinic is not just a place where Gaustine treats patients; it is also the perfect conceit for Gospodinov’s narrator to explore the 20th century in Europe through the vanishing points of traumatised or broken individuals. It’s as if Oliver Sacks and WG Sebald had collaborated on a Europe-wide chain of treatment centres.'

theguardian.com/books/2022/may

#Introduction Hi everyone, My name is Furkan. I am a last year PhD student at CerCo CNRS, Toulouse France. I am working on neural decoding and visual reconstruction from fMRI signals using deep generative models with Rufin VanRullen at #NeuroAI Lab.

I published one paper at IJCNN this year with title "Reconstruction of Perceived Images from fMRI Patterns and Semantic Brain Exploration using Instance-Conditioned GANs" in case you are interested: arxiv.org/abs/2202.12692v1

It is a pleasure to be here. I hope we can build a good community here at neuromatch.social

Good morning! It's Session 2 of #GRCdevbio23 on Metabolic fluxes in development.

Metabolic and Nutritional Control of Development and Regeneration is also the topic of
@Dev_journal
's next special issue #DevSImetabolism, which is currently being compiled:

journals.biologists.com/dev/is

A female ant bag beetle (Clytra laeviuscula), ca. 10 mm.

The larvae of this beetle develop for two years in ant colonies, during which time they eat anything they can find, from waste to ant larvae.
The adult beetles are vegetarian.

#photography #photo #nature #naturephotography #mft #microfourthirds #darktable #macrophotography #macro #nature #naturephotography #animals #wildlife #insects #beetles #chrysomelidae #clytra #clytralaeviuscula #käfer #ameisensackkäfer

'The first popular English-language science books came to India in the mid-20th century. Even today, a majority of popular science books in Indian bookstores or online marketplaces are in English and written by foreign authors. The lack of Indian stories and perspectives is stark. While bestsellers in politics, cultural fiction, entertainment, and sports dominate the Indian market and have won prestigious international awards, compelling literature on Indian science and scientists is rare. It also likely accounts for the limited penetration of any popular book on science.'

nature.com/articles/d44151-023

I second that emotion. You can know the science, have all the facts, bulletproof reasoning, and Cicero's rhetoric skills: it does not matter. There is no winning an argument with someone like this.

'You can come armed with all the facts in the world, but when you’re dealing with a conspiracist, there’s no real way to “win” an argument.'

nytimes.com/2023/06/23/opinion

It’s Not Possible to ‘Win’ an Argument With Robert F. Kennedy Jr.
“You can come armed with all the facts in the world, but when you’re dealing with a conspiracist, there’s no real way to ‘win’ an argument. For people whose views aren’t anchored to facts, winning is simply getting attention — and when you publicly argue with someone like Kennedy, you’ve already lost.”
nytimes.com/2023/06/23/opinion

#antivax #antivaxxers #science #News #USNews #Politics #USPolitics #Conspiracy

Sometimes, Wikipedia comes up trumps - thanks to Slate Weasel for putting together this comparison of some of the largest chelicerates (chelicerates = archnids and their kin) to have lived.

These little (massive) dudes and dudettes are sea scorpions, or eurypterids - probably not closelynot related to living scorpions

Last Thursday, the FDA voted to approve Sarepta's microdystrophin gene therapy for muscular .
fda.gov/news-events/press-anno

This was not an easy call, made on the basis of a biomarker rather than efficacy data. I wrote about it last month for Nature Medicine.

nature.com/articles/d41591-023

Yet another study showing that tumor mutation burden is a poor predictor of response to checkpoint blockade.

"First we assembled the largest pan-cancer dataset of immunotherapy patients with sequencing and clinical data. Surprisingly, we find little evidence that TMB is predictive of response to ICB.
(...)
Our analysis shows that the use of TMB in clinical practice is not supported by available data and can deprive patients of treatment to which they are likely to respond."

elifesciences.org/reviewed-pre

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