Thiago Carvalho @cyrilpedia@qoto.org

'Seventy-five percent of the references in NCBI/PubMed to the search word “symbiosis” (first present in 1913) have been published since 2006, as have 99% of the references to “microbiota” (first appearing in 1956). This new knowledge base will change subdisciplines of biology to varying degrees. Some areas, such as biomechanics, are likely to be little affected, but others, including immunology and developmental biology, evolutionary biology, and neurobiology, are already experiencing a reshaping as symbiosis is incorporated into their research frameworks.'

https://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.3002571

'On our trip, I finished reading Galileo: Watcher of the Skies; the author, the British historian David Wootton, does an excellent job of conjuring up the intellectual world that produced Galileo. It was a crowded community of scholars who championed many different views about how the world worked. Some became Galileo's champions, others his rivals. Wootton makes it clear that Galileo was a part of that world, not floating above it.'
@Carl_Zimmer

https://buttondown.email/carlzimmer/archive/fridays-elk-april-13-2024/

Not all heroes have capes. Some have corkscrews

“We wanted to open a restaurant that was different from the others,” he said. “So we picked this format – customers can choose to renounce technology while enjoying a convivial moment together.

https://www.theguardian.com/world/2024/apr/15/restaurant-in-italy-offers-free-bottle-of-wine-to-customers-who-hand-in-phone

'In the present study, we screened a large-scale randomly mutagenized mouse library by electrocardiography to establish a disease model of IASs and consequently found one pedigree that exhibited spontaneous ventricular arrhythmias (VAs) followed by SCD within 1 y after birth.'

https://www.pnas.org/doi/10.1073/pnas.2218204121

"Compared to 2021, we now have almost seven times as many editors in Latin America and more than five times as many in Africa. Specifically, while Latin American and African editors combined made up less than 1% of our editorial board in our last report, currently 7% of eLife editors are based in Latin America and 3% are based in Africa (Figure 1). The number of eLife editors in Asia has also grown, at the moment constituting 14% of our editorial board compared to 11% in 2021."

https://elifesciences.org/inside-elife/e3b5c5c9/elife-latest-2024-update-on-the-diversity-of-our-editorial-community

"Liz Truss’s memoir, Ten Years to Save the West, first penetrated the nation’s consciousness with her reflections on the death of Queen Elizabeth II. “Why me?” the former prime minister wrote. “Why now?” It was actually pretty funny, the depth and shamelessness of her narcissism; so funny, in fact, that I felt that, somewhere along the line, she had been stitched up by an editor. Fair play; I too would stitch her up in that job."

https://www.theguardian.com/politics/commentisfree/2024/apr/15/the-greatest-mystery-of-modern-politics-liz-trusss-self-belief

Crane on the Kamo
#kyoto

'Here we implemented two orthogonal approaches to investigate AIRE’s cis-regulatory mechanisms: construction of a convolutional neural network and leveraging natural genetic variation through analysis of F1 hybrid mice. Both approaches nominated Z-DNA and NFE2–MAF as putative positive influences on AIRE’s target choices'
#Immunology
https://www.nature.com/articles/s41586-024-07169-7

'Para que exista experimentação animal, tem obrigatoriamente de existir primeiro uma aprovação ética. Assim, todos os cientistas descrevem o projeto ao detalhe, explicando cada procedimento que será feito nos animais, o objetivo de cada experiência e os novos resultados que se esperam obter. Este documento é avaliado por uma comissão de ética, que analisa o cumprimento de leis, normas e regulamentos aplicados no projeto'

https://www.publico.pt/2024/04/14/ciencia/opiniao/filme-ratinhos-laboratorio-2086762