Thiago Carvalho @cyrilpedia@qoto.org

'Researchers performed a systematic assessment of the circular DNA structures by analysing more than 2,500 plasmids produced in labs and sent to a company that provides services such as packaging the structures inside viruses so they can be used as gene therapies. The team found that nearly half of the plasmids had design flaws, including errors in sequences crucial to expressing a therapeutic gene.'
https://www.nature.com/articles/d41586-024-02280-1

"I would also like to thank the various astronomers who forgot to collect their desserts from the fridge over the years (they were not wasted).
Roberto Soria
'Accretion processes in black-hole binaries (1999)'"

https://science.anu.edu.au/news-events/news/unexpected-poetry-phd-acknowledgements#testtube-quote-7

#Switzerland mandates #OpenSource software for all public software!

This makes perfect sense. Public software should be transparent. #India could have taken a lead on this, but our digital public infrastructure is mostly closed-source - with predictable consequences. 🙄

https://joinup.ec.europa.eu/collection/open-source-observatory-osor/news/new-open-source-law-switzerland

Postdoc in the Kwok Lab, City University of Hong Kong

City University of Hong Kong

Postdoc recruitment in Prof. Chun Kit Kwok’s lab at the City University of Hong Kong (Chemistry and Biology background)

See the full job description on jobRxiv: https://jobrxiv.org/job/city-university-of-hong-kong-27778-postdoc-in-the-kwok-lab-city-university-of-hong-kong-5/?feed_...
https://jobrxiv.org/job/city-university-of-hong-kong-27778-postdoc-in-the-kwok-lab-city-university-of-hong-kong-5/?feed_id=78609

Let me tell you this. If the pundits and media still want to play games and now come after Kamala, we've got to protest and picket them. This is not some game, some Aaron Sorkin B-movie (I'm talking to you NY Times).

Major story being mostly ignored by the media.
JD Vance left his Venmo contacts list public and people are going through it. JD's Venmo list shows 200 major donors, operatives, including dozens of RW billionaires he publicly calls the 'elites', January 6 funders, and the architects of Project 2025.
Among his 'friends list' is Amalia Halikias, Director at the Heritage Foundation—the conservative think tank coordinating the controversial Project 2025.

https://www.wired.com/story/jd-vance-venmo/

“We call it ‘generative’ but AI art can't generate the kind of turnover that aerates the aesthetic soil. An artform that can't be transgressive is sterile, stillborn, a dead end.” - @pluralistic

https://pluralistic.net/2024/07/20/ransom-note-force-field/#antilibraries

The Earth's mean temperature has a seasonal cycle that generally peaks in July, during Northern Hemisphere summer.

June 2024 was so warm that it not only exceeded every previously measured June, but also exceeded every previous July except for July 2023.

https://berkeleyearth.org/june-2024-temperature-update/

#globalwarming #climatechange #climate #temperature #records

If you’re more offended by me saying “fuck” in an essay about mass deportation than you are by the concept of mass deportation I am here to tell you to fuck the fuck off.

"We call it "generative" but AI art can't generate the kind of turnover that aerates the aesthetic soil. An artform that can't be transgressive is sterile, stillborn, a dead end."- @pluralistic https://pluralistic.net/2024/07/20/ransom-note-force-field/

COVID is still spreading, with many suffering from #SARSCoV2 infections - including @JoeBiden, 'who has encountered KP.2.3 variant and [was] still experiencing a loose, non-­productive cough and hoarseness, and has had six doses of Paxlovid.'
@WhiteHouse
https://www.whitehouse.gov/wp-content/uploads/2024/07/Letter7.20.24.pdf

Priceless!

Viktor Orbán has reached the find out phase: After two years of Orbán siding with Putin, Ukraine decided to block Russian pipeline fuel from reaching Hungary, throwing the country into a serious energy crisis.

The Hungarian people needs to elect better leaders.

https://kyivindependent.com/ukraines-sanctions-on-russias-lukoil-may-result-in-fuel-crisis-in-hungary-politico-reports/

Collection of information and links here for others to use.

Microsoft's statement: https://blogs.microsoft.com/blog/2024/07/20/helping-our-customers-through-the-crowdstrike-outage/

What happened:
https://www.crowdstrike.com/falcon-content-update-remediation-and-guidance-hub/

1/5

This cop just got charged with murder. They were supposed to release body cam footage today but instead they announced the murder charge and pushed back the video release to Monday.

#SonyaMassey called police cuz she thought someone was breaking into her home. 2 cops show up, find nothing, and then kill her.

https://newschannel20.com/news/local/deputy-faces-murder-charges-in-death-of-sonya-massey-body-cam-footage-to-be-released

'Dr. Bengt Samuelsson, a biochemist who shared the 1982 Nobel Prize in medicine for helping to define the biological activities of potent hormone-like molecules in the body called prostaglandins, and whose breakthrough discoveries led to drugs that treat inflammation, glaucoma and allergies, died on July 5 at his home in Molle, on the west coast of Sweden. He was 90.'
https://www.nytimes.com/2024/07/15/science/bengt-samuelsson-dead.html

'The Court of Justice of the European Union has ruled today that the European Commission did not give the public “sufficiently wide access” to Covid-19 vaccine contracts, finding irregularities in its justification for redacting parts of the documents.'
https://www.politico.eu/article/eus-top-court-rules-against-european-commission-in-vaccine-contracts-transparency-case/

'Women taking the anti-diabetes medication Ozempic might have an extra reason to pat their tummies. Not only does the injectable drug lead to weight loss, a finding that has sparked frenzied off-label demand worldwide, but in recent months it has also been linked to a surprise baby boom.'
https://www.ft.com/content/bf52faa7-9428-450f-a1f6-69fde3fa4c51

'The Electronic Bard is not easy for Trurl to make. In thinking about how to program it, Trurl reads “twelve thousand tons of the finest poetry” but deems the research insufficient. As he sees it, the program found in the head of even an average poet “was written by the poet’s civilization, and that civilization was in turn programmed by the civilization that preceded it, and so on to the very Dawn of Time.” The complexity of the average poet-machine is daunting.'
https://www.newyorker.com/science/elements/thinking-about-ai-with-stanislaw-lem

"Concomitant to the unravelling of bacterial immune defence was the realisation that some antiphage systems are in fact conserved in eukaryotes [7–9]. For example, cyclic GMP-AMP synthase (cGAS)-like enzymes, which produce cyclic dinucleotide second messengers upon pathogen detection, and viperins, which generate modified nucleotides blocking viral replication, protect bacteria and humans alike. Contrary to the conceptual framework of clade-specific immune mechanisms, a fraction of immune modules (domains or proteins involved in defence) are conserved between prokaryotes and eukaryotes."
https://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.3002717