Seipin Regulates Caveolin-1 Trafficking and Organelle Crosstalk https://www.biorxiv.org/content/10.1101/2024.09.17.613438v1?med=mas
The lysosomal membrane protein LAMP2B mediates microlipophagy to target obesity-related disorders https://www.biorxiv.org/content/10.1101/2024.09.18.613587v1?med=mas
'But it’s important to consider our history. In 1791, Haitians successfully rebelled against the French colonizers, sparking a resistance that would lead to the country being the first free Black nation in the Western Hemisphere. In the ensuing two hundred and thirty-two years and change, the rest of the world has seemed hellbent on making Haiti pay, for fear of global Black liberation.'
https://www.newyorker.com/news/the-lede/the-haitian-question
Emperor Go-Murakami, 97th Emperor of #Japan, ascended to the Chyrsanthemum Throne OTD in 1339 https://cromwell-intl.com/travel/japan/kofun/konabe.html?s=mb #travel #history
Explore the exquisite craftsmanship of Yohei II's dining set, featuring delicate plum blossoms and the unique cracked-ice motif. Each piece tells a story of artistry and history. What draws you to this harmonious blend of function and beauty?
#JapaneseArt #Ceramics #ClevelandArt
https://clevelandart.org/art/2022.150.24.a
"Nigel Farage Goes on Pro-Fossil Fuel Rant at Fundraiser for Climate Denial Group"
'Here, we chose to study how centrosome amplification influences the response to combined Carboplatin and Paclitaxel in the context of epithelial ovarian cancer, a disease with poor clinical outcome related to late diagnosis, and frequent relapse'
https://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.3002759
Scientific American review of my forthcoming book, "Dr. Calhoun’s Mousery"
"A new biography nearly as quirky as its subject. Dugatkin—an evolutionary biologist, science historian and prolific author who sifted through thousands of pages at the Calhoun archive in Bethesda—is an admirably thorough researcher......Dugatkin captures the grand ambition of a man who gazed at rodents and saw the universe..."
Virus that causes paralyzing illness is spiking in the U.S., wastewater data shows.
NBC News reports: "Enterovirus D68 is linked to rare cases of the polio-like illness acute myelitis, or AFM. So far this year, the CDC has confirmed 13 cases of AFM."
A rare flip in wind direction contributed to record flooding in the Carolinas, and an atmospheric block caused catastrophic flooding in Europe. Weird weather explained here: https://www.scientificamerican.com/article/record-breaking-rainfall-in-carolinas-and-europe-explained/
"Captain Needa had meant well. He and those in his command on an Imperial Star Destroyer ship were pursuing the Millennium Falcon when it inexplicably disappeared. Taking sole responsibility, he said that he alone would apologize to Darth Vader."
https://www.nytimes.com/2024/09/16/movies/star-wars-actors.html
@GottaLaff Hate to say, it's happening everyday and everywhere! The GQP Domestic Terrorists are stoking fear and violence across the Country. I'm Central Florida as I write this, another school has been evacuated this morning from threats. Last week my Daughter's old HS was on full lockdown because a 15 year old brought a loaded gun to school. Seminole County next to my Orange County had several lockdowns and evacuations last week. This is disgusting and preventable. The Right is 100% doing it!!
People Living with Sickle Cell Disease Share Their Experiences
Such an interesting, thoughtful response to LLMs eating the world from authoring app iA...
Instead of jumping on the bandwagon to integrate LLMs to create your content, it tracks the provenance of your text instead, letting you keep track of what's yours and what isn't.
An elegant, contrarian strategy. HT @marcoshuerta
Testing the hypothesis that "despite the rapid evolution of reproductive protein genes, the functional basis of metazoan male germ cell identity relies on an old, evolutionarily conserved genetic program that can provide relevant insight into spermatogenesis and human infertility."
Leaked Supreme Court memos reveal John Roberts' role in shielding Trump from prosecution
https://www.salon.com/2024/09/16/leaked-memos-reveal-john-roberts-role-in-shielding-from-prosecution
* SCOTUS Chief Justice John Roberts
* 2024-Feb-22 issued memo urging SCOTUS justices not only to take up an appeal f. former President Trump over his immunity claim, but also to rule in favor of granting Trump that immunity
* “I think it likely that we will view the separation of powers analysis differently” from the appeals court
STAT+: Pharmalittle: We're reading about an Express Scripts lawsuit against FTC, AMR deaths, and more
Women In Georgia Are Literally Dying Because Of Stupid And Cruel Abortion Laws
https://www.wonkette.com/p/women-in-georgia-are-literally-dying
'We now report that efferocytosis triggers an indoleamine 2,3-dioxygenase-1 (IDO1)-dependent tryptophan (Trp) metabolism pathway that promotes several key resolution processes, including the induction of pro-resolving proteins, such interleukin-10, and further enhancement of efferocytosis.'
#Immunology
https://www.nature.com/articles/s42255-024-01115-7?utm_source=dlvr.it&utm
North American bats are being decimated by a lethal fungus. Here's my story about how scientists are fighting back--and finding hope. Gift link: https://nyti.ms/3XHWsqd [Photo by Graham Dickie]
I've worked on all of science, from B cells to T cells.
https://fellowsherpa.com