Show newer

Microbiome stability is linked to coral thermotolerance biorxiv.org/content/10.1101/20

Microbiome stability is linked to coral thermotolerance

Corals associate with a diverse community of prokaryotic symbionts that provide nutrition, antioxidants, and other protective compounds to their host. However, the influence of microbes on coral thermotolerance remains understudied. Here, we examined the prokaryotic microbial communities associated with colonies of Acropora cf. tenuis that exhibit high or low thermotolerance upon exposure to 33°C (heated) relative to 29°C (control). Using 16S rRNA sequencing, we show that the microbial community structure of all A. cf. tenuis colonies were similar at control temperature. Thermotolerant colonies, however, had relatively greater abundance of Endozoicomonas, Arcobacter, Bifidobacterium and Lactobacillus. At elevated temperature, only thermosensitive colonies showed a distinct shift in their microbiome, with an increase in Flavobacteriales, Rhodobacteraceae, and Vibrio, accompanying a marked bleaching response. Functional prediction indicated that prokaryotic communities associated with thermotolerant corals were enriched for genes related to metabolism, while microbiomes of thermosensitive colonies were enriched for cell motility and antibiotic compound synthesis. These differences may contribute to the variable performance of thermotolerant and thermosensitive corals under thermal stress. Identification of microbial taxa correlated with thermotolerance provides insights into beneficial bacterial groups that could be used for microbiome engineering to support reef health in a changing climate. ### Competing Interest Statement The authors have declared no competing interest.

bioRxiv

The NY Times article without paywall.

**‘Buying Quiet’: Inside the Israeli Plan That Propped Up Hamas**

*Prime Minister Benjamin Netanyahu gambled that a strong Hamas (but not too strong) would keep the peace and reduce pressure for a Palestinian state.*

archive.is/zwo64

I don't follow closely this conflict. But is this raised more often? How can you support the very simple idea of financing a terrorist group that wants your destruction? This policy of Netanyahu is simply sick to me and looks like coming from a psychopath. I cannot find a better word.

Do powerful rightwing extremists in the government of Israel really want to have Arabs and Israeli killing each other on the streets? The documentary I recommended also suggests this idea.

#netanyahu #hamas #qatar #terrorism #NetanyahuWarCriminal #Gaza

'In this randomized, controlled trial involving women in South Africa and Uganda, twice-yearly subcutaneous lenacapavir was superior to daily oral emtricitabine–tenofovir disoproxil fumarate in preventing HIV infection.'

nejm.org

"Nas instituições científicas portuguesas há cerca de 3000 contratos a termo, com o seu fim previsto para os próximos anos. Na verdade, destes, há 1607 vínculos de cientistas que terminarão até 2026 e que, no próximo ano, terão de encontrar soluções se quiserem continuar o seu percurso enquanto investigadores em Portugal. Já no primeiro semestre deste ano, 676 cientistas viram o seu vínculo terminar depois de assinar um contrato pelo regime da norma transitória."
publico.pt/2024/10/03/ciencia/

"With the most potent weight-loss shot and a pipeline of 11 experimental treatments, including what is widely expected to be the first approved small molecule GLP-1 pill, Eli Lilly stands to be the biggest winner in a market that is projected to grow to $130bn a year in peak sales by the end of the decade"

ft.com/content/ed81ca79-1fd6-4

'Oncogenic PIK3CA mutations generate large clones in aging human esophagus. Here we investigate the behavior of Pik3ca mutant clones in the normal esophageal epithelium of transgenic mice. Expression of a heterozygous Pik3caH1047R mutation drives clonal expansion by tilting cell fate toward proliferation'

nature.com/articles/s41588-024

Is there a self-help group for “I ran an #AlphaFold 3 prediction and it is fundamentally different to the AF2 prediction”? Asking for a friend.

#LabLife

'Oncogenic PIK3CA mutations generate large clones in aging human esophagus. Here we investigate the behavior of Pik3ca mutant clones in the normal esophageal epithelium of transgenic mice. Expression of a heterozygous Pik3caH1047R mutation drives clonal expansion by tilting cell fate toward proliferation'

nature.com/articles/s41588-024

We’ve reached 10,000 submissions to the eLife Model 🥳

So, we thought we’d reflect on how the model is making a positive impact, and highlight some author feedback from their experience of publishing with us.

And if you’d like to know more about how submitting to the eLife Model works, take a look at our video on YouTube!
elifesciences.org/inside-elife

youtu.be/XVnJVPj23ig

A group of 2024 ASAPbio Fellows are currently conducting a survey on the experiences of crowd reviewers with the Crowd Preprint Review Program. To celebrate peer review week we've released a sneak peak at some of our findings!

Read more in our blog post: buff.ly/4dnG4Qp

Getting ready for our open day tomorrow, I've updated a couple of my old maths trick webpages.

The incredible palindromic hat-trick now has scroll-snap so it's a bit easier to read through: somethingorotherwhatever.com/s

The "I can name your polynomial" trick now uses built-in BigInts and uses MathML instead of MathJax: somethingorotherwhatever.com/n

'Because Facebook wanted to show that its algorithm was not increasing polarization, it made claims that both Science and the authors saw as unsupported by the research. The global affairs president of Meta (Facebook’s parent company), Nick Clegg, said that the papers undermined claims that the site was designed to “serve people content that keeps them divided,” while author Natalie Jomini Stroud countered that Clegg had overstated the extent to which the study can be interpreted in Facebook’s favor.'

science.org/doi/10.1126/scienc

COVID tests are expensive in the US, and you never know when you'll need them; it's best to always have them on hand and ready to go.

So please don't delay, order your 4 free COVID tests (which will be sent to you through the mail) now: covidtests.gov

'Spectacular breakthroughs in science can’t benefit people without translation to populations. To quote Paul Farmer, “In an age of explosive development in the realm of medical technology, it is unnerving to find that the discoveries of Salk, Sabin, and even Pasteur remain irrelevant to much of humanity.'

nejm.org/doi/full/10.1056/NEJM

Show older
Qoto Mastodon

QOTO: Question Others to Teach Ourselves
An inclusive, Academic Freedom, instance
All cultures welcome.
Hate speech and harassment strictly forbidden.