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'Think about it: fakery is what AI image-generating systems do; it's their entire raison d'être. You give them prompts so that they will whip up something plausible, something that looks like what you wanted. So whip me up a good looking Western blot, or maybe just a selection of good-looking bands that I can use in my Frankensteined Westerns where they won't appear duplicated!'

science.org/content/blog-post/

“for women in biology, the likelihood of leaving science after ten years was 58%; for men, it was nearly 49%.”

Nearly 50% of researchers quit science within a decade, huge study reveals

nature.com/articles/d41586-024

The NY Times article without paywall.

**‘Buying Quiet’: Inside the Israeli Plan That Propped Up Hamas**

*Prime Minister Benjamin Netanyahu gambled that a strong Hamas (but not too strong) would keep the peace and reduce pressure for a Palestinian state.*

archive.is/zwo64

I don't follow closely this conflict. But is this raised more often? How can you support the very simple idea of financing a terrorist group that wants your destruction? This policy of Netanyahu is simply sick to me and looks like coming from a psychopath. I cannot find a better word.

Do powerful rightwing extremists in the government of Israel really want to have Arabs and Israeli killing each other on the streets? The documentary I recommended also suggests this idea.

#netanyahu #hamas #qatar #terrorism #NetanyahuWarCriminal #Gaza

'In this randomized, controlled trial involving women in South Africa and Uganda, twice-yearly subcutaneous lenacapavir was superior to daily oral emtricitabine–tenofovir disoproxil fumarate in preventing HIV infection.'

nejm.org

"Nas instituições científicas portuguesas há cerca de 3000 contratos a termo, com o seu fim previsto para os próximos anos. Na verdade, destes, há 1607 vínculos de cientistas que terminarão até 2026 e que, no próximo ano, terão de encontrar soluções se quiserem continuar o seu percurso enquanto investigadores em Portugal. Já no primeiro semestre deste ano, 676 cientistas viram o seu vínculo terminar depois de assinar um contrato pelo regime da norma transitória."
publico.pt/2024/10/03/ciencia/

"With the most potent weight-loss shot and a pipeline of 11 experimental treatments, including what is widely expected to be the first approved small molecule GLP-1 pill, Eli Lilly stands to be the biggest winner in a market that is projected to grow to $130bn a year in peak sales by the end of the decade"

ft.com/content/ed81ca79-1fd6-4

'Oncogenic PIK3CA mutations generate large clones in aging human esophagus. Here we investigate the behavior of Pik3ca mutant clones in the normal esophageal epithelium of transgenic mice. Expression of a heterozygous Pik3caH1047R mutation drives clonal expansion by tilting cell fate toward proliferation'

nature.com/articles/s41588-024

Is there a self-help group for “I ran an #AlphaFold 3 prediction and it is fundamentally different to the AF2 prediction”? Asking for a friend.

#LabLife

“Patterns were taken up as rules to govern design, or instructions to be implemented, rather than as a compendium of examples derived from Alexander’s deeper insight into The Timeless Way of Building. This problem stalked the pattern language approach in almost all disciplines, eventually turning the promising efforts pattern-languaging communities into…exercises in pattern-matching abstractions.”
—Bonnitta Roy
bonnittaroy.substack.com/p/chr
#pattern #patternlanguage #christopheralexander

'Oncogenic PIK3CA mutations generate large clones in aging human esophagus. Here we investigate the behavior of Pik3ca mutant clones in the normal esophageal epithelium of transgenic mice. Expression of a heterozygous Pik3caH1047R mutation drives clonal expansion by tilting cell fate toward proliferation'

nature.com/articles/s41588-024

We’ve reached 10,000 submissions to the eLife Model 🥳

So, we thought we’d reflect on how the model is making a positive impact, and highlight some author feedback from their experience of publishing with us.

And if you’d like to know more about how submitting to the eLife Model works, take a look at our video on YouTube!
elifesciences.org/inside-elife

youtu.be/XVnJVPj23ig

A group of 2024 ASAPbio Fellows are currently conducting a survey on the experiences of crowd reviewers with the Crowd Preprint Review Program. To celebrate peer review week we've released a sneak peak at some of our findings!

Read more in our blog post: buff.ly/4dnG4Qp

The clock is ticking for women in Japan who missed out on the human papillomavirus vaccine to get it for free — the first dose must be administered by the end of September to complete the three-dose series before the campaign ends in six months. japantimes.co.jp/news/2024/09/ #japan #sciencehealth #vaccines #hpv #health

Is this the creepiest fungus in the forest? Yes, definitely.

From @popsci: "The 'immortal' Dead man's fingers fungus won't eat your brain, just dead wood."

flip.it/X4Ad_g

#Fungus #Plants #Biology #Botany #Science

Getting ready for our open day tomorrow, I've updated a couple of my old maths trick webpages.

The incredible palindromic hat-trick now has scroll-snap so it's a bit easier to read through: somethingorotherwhatever.com/s

The "I can name your polynomial" trick now uses built-in BigInts and uses MathML instead of MathJax: somethingorotherwhatever.com/n

'Because Facebook wanted to show that its algorithm was not increasing polarization, it made claims that both Science and the authors saw as unsupported by the research. The global affairs president of Meta (Facebook’s parent company), Nick Clegg, said that the papers undermined claims that the site was designed to “serve people content that keeps them divided,” while author Natalie Jomini Stroud countered that Clegg had overstated the extent to which the study can be interpreted in Facebook’s favor.'

science.org/doi/10.1126/scienc

COVID tests are expensive in the US, and you never know when you'll need them; it's best to always have them on hand and ready to go.

So please don't delay, order your 4 free COVID tests (which will be sent to you through the mail) now: covidtests.gov

'Spectacular breakthroughs in science can’t benefit people without translation to populations. To quote Paul Farmer, “In an age of explosive development in the realm of medical technology, it is unnerving to find that the discoveries of Salk, Sabin, and even Pasteur remain irrelevant to much of humanity.'

nejm.org/doi/full/10.1056/NEJM

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