Thiago Carvalho @cyrilpedia@qoto.org
I've worked on all of science, from B cells to T cells.
https://fellowsherpa.com
Joined Nov 2022
“There were really compelling videos shown of kids running upstairs, kids swimming, jumping off a platform into water. You would not be a human being if you did not react in an excited way to those . . . But the primary endpoint in the clinical trial was not met.”
https://www.ft.com/content/19d3aa5f-321b-4ec1-a620-6860ad089c55
Thiago Carvalho
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Postdoctoral Researcher
University of Hawaii Cancer Center
Exciting NIH-Funded Postdoctoral Fellowship Opportunity: Advance the Battle Against Aggressive Breast Cancers
See the full job description on jobRxiv: https://jobrxiv.org/job/university-of-hawaii-cancer-center-27778-postdoctoral-researcher/?feed_id=48145
#ScienceJobs #hiring #research
Hawaii/Honolulu #UnitedStatesUS #Postdoct...
https://jobrxiv.org/job/university-of-hawaii-cancer-center-27778-postdoctoral-researcher/?feed_id=48145
Thiago Carvalho
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1963 | J.Monod, F. Jacob, and Changeux describe an allosteric mechanism to explain regulation and cooperativity in enzymes by ligands that bind to a protein on a location different from the active site | #proteomics
Thiago Carvalho
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Scientists ran a health check on the Earth — and the results are worrying https://www.washingtonpost.com/science/2023/06/02/earth-commission-climate-pollution-limits/
How can we forge a consensus and common belief in the need to manage our impact on our (only) home?
Thiago Carvalho
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@cyrilpedia I'm always surprised when people think they have a single strategy like this that works (I've heard plenty of others espouse this approach).
To me, knowing what works for whom is the real skill. Alex Ferguson did it best. His genius was "knowing which players need an arm round the shoulders and which need a kick up the arse".
Thiago Carvalho
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what a surprise, the vile Boris breached the ministerial code in accepting new job at the Daily Hate https://theguardian.com/politics/live/2023/jun/16/boris-johnson-partygate-report-rishi-sunak-damian-green-vote-conservatives-uk-politics-live
Meant to clear new jobs with committee to avoid former ministers cashing in on their previous govt job, Boris only told them 30 mins beforehand... Total disdain for rules and expected behaviour by an entitled bilgebag.
Thiago Carvalho
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An interview with Elaine Fuchs.
We talk about stem cell niches in the skin, tissue regeneration and how skin cell chromatin remembers stress experienced.
Elaine foresees a time when the concept of "memory" extends beyond neurons.
Thiago Carvalho
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"Shouldn’t pay-for-delay agreements be a clear antitrust violation? According to a group of plaintiffs that include prominent HIV/AIDS advocates, the answer is yes."
https://www.theatlantic.com/ideas/archive/2023/06/pharmaceutical-generic-drugs-pay-for-delay/674410/
Thiago Carvalho
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Looking objectively, RFK Jr is a conspiracy theorist and crank who thinks the CIA runs The Daily Beast and 5G is a government mind-control plot
https://popular.info/p/fox-news-favorite-democratic-presidential
Thiago Carvalho
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@cyrilpedia Interesting. I remember a friend from Nature (years ago) saying that the culture there was to always have people slightly outside their comfort zone. I asked an HR person (at a different organization) about this strategy, and she said it was a well known (male) macho strategy that ultimately produced staff disharmony and didn't actually make people perform better.
Thiago Carvalho
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Thiago Carvalho
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«Sous le regard de Méduse» à #Caen : the show must Gorgone Adorée des artistes et devenue icône féministe, la fascinante monstre de la mythologie grecque aux yeux pétrificateurs est célébrée dans une expo au musée des Beaux-Arts de @CaenOfficiel. Lire : https://www.liberation.fr/culture/arts/sous-le-regard-de-meduse-a-caen-the-show-must-gorgone-20230617_VET5CYZFEJF2NMUKBCVAVLFSQA/?utm_medium=Social&utm_source=Mastodon
Thiago Carvalho
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Research Staff Assistant
Zuckerman Institute, Columbia University
See the full job description on jobRxiv: https://jobrxiv.org/job/research-staff-assistant-9/?feed_id=47921
#ScienceJobs #hiring #research
New York City #UnitedStatesUS #ResearchAssistant #ResearchTechnician #Researcher
https://jobrxiv.org/job/research-staff-assistant-9/?feed_id=47921
Thiago Carvalho
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Poly(A)-binding protein is an ataxin-2 chaperone that regulates biomolecular condensates https://www.cell.com/molecular-cell/fulltext/S1097-2765(23)00381-7?rss=yes&utm_source=dlvr.it&utm_medium=mastodon
There's more to gasdermin than just proptosis.
'Our study supports that differential cleavage of GSDMD can be understood as a regulatory hub controlling immunity versus tolerance in the small intestine.'
#Immunology #mucosalimmunology
'The results highlight how widely and unpredictably disease severity and contagiousness vary between people. “And it’s that variability among humans that has made this virus so difficult to control,” says infectious-disease doctor Monica Gandhi at the University of California, San Francisco, who was not involved in the work. The study, published on 9 June in Lancet Microbe, also suggests that human physiology, not the virus, is to blame for some of the inconsistency of COVID-19'
'As science becomes increasingly accessible to the general public, racist agendas can now more easily use science to disinform. All scientists must pursue and accomplish anti-racism efforts to achieve change at the system level. Juneteenth can remind us of what we still need to change, but doing so requires action from funding bodies, institutions, and the wider community.'
JM Keynes FTW
"He championed better statistics and secured the appointment of a statistician to the department, but he also came to doubt the excessive claims statisticians made for quantitative knowledge. Too often, he thought, they slid unwittingly from precise description to sweeping interpretation. Numbers were essential to knowledge, but when they acquired a fetish-like quality they led to intellectual laziness—creating an aura of precision around unwarranted claims, fostering fantasies of control over the future."
https://www.commonwealmagazine.org/john-maynard-keynes-economics-uncertainty-woolf-lears
Thiago Carvalho
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Portrait of the artist making last minute adjustments. Congratulations to @madparreira @anaanajottajotta @jorgenesbitt @consta_arouca on a very successful opening. If you couldn't make it last night, 'Oubliette' will be at Biblioteca Camoes in Lisbon until June 30th.
#Art #artmastodon #artgallery
Thiago Carvalho
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Time to develop fire-resistant yellowtips:
"As Roma Agrawal explains in her new delightful book Nuts and Bolts, early 17th-century Virginians would sometimes burn down their homes if they were planning to relocate. This was an attempt to recover the valuable nails, which could be reused after sifting the ashes. The idea that one might burn down an entire house just to reclaim the nails underlines how scarce, costly and valuable the simple-seeming technology was."
https://www.ft.com/content/4240569a-aa55-468e-8dc4-2953612c38d1
I've worked on all of science, from B cells to T cells.
https://fellowsherpa.com
Joined Nov 2022
