Thiago Carvalho @cyrilpedia@qoto.org

Now out in @CurrentBiology -- our paper on cortical pattern amplification with learning, w/ @KanakaRajanPhD 🧠📄

Below in thread: Huge perceptual improvement. No vis resp changes. Simple recurrent model. Relationship to recent S. Peron lab paper. +more.

What does it mean? Biological recurrent networks in vivo can change to accommodate totally new patterns of input. We provide those artificially w/ optogenetics.

1/ #neuroscience #ai #postprint

All you need to know about how rentier #capitalism works in one but of data:

The UK's water firms were privatised without any outstanding debts over thirty years ago.... now, the privatised #infrastructure (regional) #monopolies have around £62bn in debt, but are still failing to deliver an adequate service.

If that debt has not been used to invest sufficiently in the #infrastructure, which the firms now (grudgingly) admit,, you might wonder where has it gone?

I leave that for you to guess!

Ever wondered what a baby #scorpion looks like? Wonder no more! This is the first instar pronymph of scorpion species Centruroides vittatus (the striped bark scorpion).

Image from Farley, R.D., 2005. Developmental changes in the embryo, pronymph, and first molt of the scorpion Centruroides vittatus (Scorpiones: Buthidae). Journal of Morphology, 265(1), pp.1-27.

#science #arachnids

On this day in 1869: Hans Spemann born, won 1935 #NobelPrize for discovering embryonic induction #ThisDayInBiotech

Hi #ScienceMastodon. We, @Dev_journal are a community journal covering all areas of #devbio. Development is led by Editor-in-Chief James Briscoe & published by the not-for-profit @Co_Biologists.

We will toot about #research papers, #reviews, #interviews, charitable activities, and news from @the_node.

We’ve moved over to our own instance @biologists.social, & hope that you’ll join us there for friendly chats between biologists!

https://biologists.social/about

Mais uma vez, a direita juntou-se à extrema-direita contra a proteção do ambiente, acenando a mentira e a chantagem sobre a crise para boicotar a ação. Quando é para ir além dos discursos genéricos, a direita nunca falha. Ou melhor, falha sempre.
<div class="rsshub-quote">
Marisa Matias: O voto da 🌱Lei do Restauro da Natureza, hoje na @ENVI, foi uma clarificação entre quem defende o futuro e quem não têm qualquer tipo de escrúpulos na defesa dos interesses económicos que trouxeram o planeta ao estado em que se encontra.
#RestoreNature 🧵 https://t.co/y2kNikZlkp
</div>

🐦🔗: https://n.respublicae.eu/joseggusmao/status/1673651628434415616

On #TechnicalTuesday we’re highlighting the OptIC-Notch tool from Jonathan Townson, Sarah Bray and colleagues based on the BLITz approach. The authors used this optogenetic method to temporally interrogate the interaction between Notch intracellular domain and the DNA-binding transcription factor CSL.

📖@Dev_journal: https://journals.biologists.com/dev/article/150/11/dev201785/316612/OptIC-Notch-reveals-mechanism-that-regulates

#microscopy #devbio

Hi #ScienceMastodon.

#preLights (https://prelights.biologists.com) is a #preprint highlights service run by the biological #community & supported by #Co_Biologists allowing one to:

🔎 Sift through the high # of preprints.
💡 Highlight new thinking/techniques across the biological sciences.
📝 Comment on preprints.
👥 See comments & opinions of others.

We’ve moved over to our own instance @biologists.social, & hope that you’ll join us there for friendly chats between biologists!

https://biologists.social/about

Looks interesting, Heng Li proposes a faster #BUSCO: "miniBUSCO achieves a 14-fold speedup over BUSCO. Furthermore, miniBUSCO reports a more accurate completeness of 99.6% than BUSCO’s completeness of 95.7%, which is in close agreement with the annotation completeness of 99.5% for T2T-CHM13"
https://www.biorxiv.org/content/10.1101/2023.06.03.543588v1 #bioinformatics #HumanGenome #genomics

At #GRCdevbio23,
@tinalab_inStem (@DBT_inStem) brings together metabolism, growth and the immune system.

Learn more about Tina's work with
@m_goyal08 and colleagues in
@Dev_journal: https://journals.biologists.com/dev/article/149/8/dev199550/273541/Blood-progenitor-redox-homeostasis-through

Hi #ScienceMastodon. @focalplane_jcs is your #microscopy community site hosted by @J_Cell_Sci & @Co_Biologists, connecting people, resources & info.
Anyone can contribute on https://focalplane.biologists.com. We’ll be tooting the latest news & posts from the #community. You can also join and use the FocalPlane Network to make new connections.

We’ve just moved over to our own instance @biologists.social, & hope that you’ll join us there for friendly chats between biologists!
https://biologists.social/about

Hungarian Prime Minister Viktor Orban said that Russian President Vladimir Putin, in his opinion, is not a war criminal. Putin puppet Orban needs to be made to heel. NATO needs a suspension and removal mechanism for when states no longer meet requirements.
#StandWithUkraine

Hi #ScienceMastodon. We, @J_Cell_Sci, are a community journal covering all areas of #cellbiology. Journal of Cell Science is led by Editor-in-Chief Michael Way & published by the not-for-profit @Co_Biologists.
We will toot about our content, including #research papers, #reviews, #interviews, charitable activities, and news from @focalplane_jcs.
We’ve moved over to our own instance @biologists.social, & hope that you’ll join us there for friendly chats between biologists!
https://biologists.social/about

Hi #ScienceMastodon. The Node (https://thenode.biologists.com) is the community website for and by #devbio and #stemcell biologists, where you can read the latest news and stories, check out jobs and events pages and interact with colleagues from around the world.

The Node is run by the journal @Dev_journal and its publisher, @Co_Biologists.

We’ve moved over to our own instance @biologists.social, & hope that you’ll join us there for friendly chats between biologists!

https://biologists.social/about

PepFlow: direct conformational sampling from peptide energy landscapes through hypernetwork-conditioned diffusion | https://www.biorxiv.org/content/10.1101/2023.06.25.546443v1.full.pdf+html #proteomics

👨‍🔬👩‍🔬Together we win! Thanks to the collaboration with Università di Torino we'll be pioneering the development of advanced methods for detecting cancer biomarkers using oligonucleotide sequencing.

🔬Our #CollaborActions 👉https://humantechnopole.it/en/research/our-scientific-partnerships-collaborations/

#science #sciencemastodon #lifesciences #humantechnopole