Thiago Carvalho @cyrilpedia@qoto.org

New TG mouse model for #SARSCoV2 infection

"In this study, we report an inducible, transgenic hACE2 mouse line and showcase three examples for specifically expressing hACE2 in three different lung epithelial cells, including AT2 cells, club cells, and ciliated cells. Moreover, all these mice models develop severe pneumonia after SARS-CoV-2 infection."

https://www.pnas.org/doi/10.1073/pnas.2207210120

#Introduction

I am a #NewPI in stem cell & developed tan biology working at the Babraham Institute (Cambridge).
Will tweet about everything related with #devbio and life as an academic scientist.

Very excited that a community is built!

Americans Shocked by Audiotape Appearing to Prove Trump Capable of Reading
https://www.newyorker.com/humor/borowitz-report/americans-shocked-by-audiotape-appearing-to-prove-trump-capable-of-reading

The current structure of science funding would make Max Perutz's work impossible and Perutz unemployed:

"Max, inspired by Bernal's vision that the structure of large and complex molecules such as proteins could be solved using X-ray diffraction, embarked on scaling a mountain in biology—solving the structure of haemoglobin. This was to take him more than 20 years."

https://www.embopress.org/doi/full/10.1093/embo-reports/kvf103

Last few days to check out "Oubliette", a collective show by
@anaanajottajotta @consta_arouca @jorgenesbitt @madparreira at Biblioteca Camoes, Lisbon.
#Art #exhibition #artgallery

#sculpture #printmaking and more.

https://informacoeseservicos.lisboa.pt/contactos/diretorio-da-cidade/biblioteca-camoes

Another famous passage from Dale. The ripple and shimmer!

"If 1 gamma of acetylcholine, for example, dissolved in 0.1 cc of Ringer’s solution, is thus injected suddenly into the artery supplying the frog’s gastrocnemius, the surface of the muscle, covered with its glistening aponeurosis, shows immediately the ripple and shimmer of innumerable, unsynchronized contractions, propagated along the fibres and fascicles of the muscle"

https://www.nobelprize.org/prizes/medicine/1936/dale/lecture/

Postdoc in Host-microbe interactions – computational and/or experimental

Cornell University

See the full job description on jobRxiv: https://jobrxiv.org/job/cornell-university-27778-postdoc-in-host-microbe-interactions-computational-and-or-experimental-2/?feed_id=48572

#ScienceJobs #hiring #research
Ithaca, NY #UnitedStatesUS #PostdoctoralFellow
https://jobrxiv.org/job/cornell-university-27778-postdoc-in-host-microbe-interactions-computational-and-or-experimental-2/?feed_id=48572

#IDMastodon #Viralimmunology #Immunology #Cytokinebiology @CytokineSociety The delicate balance of the pro- & anti-inflammatory #cytokine responses that mediate effective clearance of viral titters is crucial for the effective resolution of #COVID19.
#Cytokinestorm results from disrupting this equilibrium, leading to uncontrolled immune cell responses.

One of the embryo model studies I wrote about the other day is officially published in Nature: https://www.nature.com/articles/s41586-023-06368-y And one that I didn't write about is also published there: https://www.nature.com/articles/s41586-023-06354-4 So that's 5 embryo models, w/more to come...

Watch the Building of the Eiffel Tower in Timelapse Animation

https://www.openculture.com/2021/05/watch-the-building-of-the-eiffel-tower-in-timelapse-animation.html

Lets discover all about #biology #cellbiology #neurobiology #genetics #molecular_genetics and other biology stuff!

#biology #neurobiology #genetics #dna #moleculargenetics #cellbiology #science #proscience #chemics #TheMysteriesOfScience #TheMysteriesOfGenetics #sleepyicedragon #sleepyicedragonRNDM #genes

The Company of Biologists is excited to announce the launch of its new mastodon instance @biologists.social, on which you can now find all our journals and community sites. We look forward to sharing more news about this new community in the coming days.

Back to the zebrafish fin at #GRCdevbio23, with @HeatherBleu (@uoregon) discussing the role of calcium signalling in controlling the regeneration of the size and shape of organs, using the longfin zebrafish mutant published in @Dev_journal
https://doi.org/10.1242/dev.199384

'The first popular English-language science books came to India in the mid-20th century. Even today, a majority of popular science books in Indian bookstores or online marketplaces are in English and written by foreign authors. The lack of Indian stories and perspectives is stark. While bestsellers in politics, cultural fiction, entertainment, and sports dominate the Indian market and have won prestigious international awards, compelling literature on Indian science and scientists is rare. It also likely accounts for the limited penetration of any popular book on science.'

https://www.nature.com/articles/d44151-023-00069-1