Thiago Carvalho @cyrilpedia@qoto.org
I've worked on all of science, from B cells to T cells.
https://fellowsherpa.com
Joined Nov 2022
Thiago Carvalho
boosted
Protein overabundance is driven by growth robustness https://www.biorxiv.org/content/10.1101/2024.08.14.607847v1?med=mas
'However, how IL2 function is integrated during earlier antigen-dependent T cell synapses is unknown. Here, we demonstrate a synergistic effect between the T cell receptor (TCR) and IL2 receptor signalling at the immunological synapse of CD8+ T cells with supported lipid bilayers.'
#Immunology #Preprint
Thiago Carvalho
boosted
Anomalies in regional and chronological distributions of Omicron BA.1.1 lineage in the United States https://www.medrxiv.org/content/10.1101/2024.08.14.24311991
Thiago Carvalho
boosted
Chechen dictator Ramzan Kadyrov has posted a video on social media showing off his new cybertruck. He claims that it was a gift directly from Elon Musk and vows to send the "cyberbeast" into battle against Ukraine. https://t.me/RKadyrov_95/4999
Thiago Carvalho
boosted
Here’s another Fediverse project similar to Twitter.
But the wrinkle here is that, right out of the box, you can also connect with Bluesky.
The UI is in Japanese – just remember that.
'Immunology is another jackpot area for potential buyers. London-based VC firm Medicxi assembled six immunodermatology-focused portfolio companies plus $100 million to create Alys Pharmaceuticals in February 2024. Inflammation and immunology are “attracting huge interest from pharma,” says partner Francesco de Rubertis, given the multiple indications and pathways in the space. “Obesity is hot, but much harder to break into” if you’re not already a player, he says.'
https://www.nature.com/articles/s41587-024-02357-2
Thiago Carvalho
boosted
"10 new photo negatives of post-bombing Hiroshima discovered at Mainichi's Osaka office"
https://mainichi.jp/english/articles/20240813/p2a/00m/0na/026000c
Deadline September 30, 2024
'Until 2019, the Rosalind Franklin Young Investigator Award was given every three years, to two women; since 2022, three women are selected to receive $75,000 over three years ($25,000 per year). The awards fund genetics research in human and non-human mammals, and in non-mammalian organisms'
https://genetics-gsa.org/awards/rosalind-franklin-young-investigator-award/
Thiago Carvalho
boosted
Chicago's Mayor Owes His Career to Activism. How Will He Handle Demonstrators at the DNC?
Thiago Carvalho
boosted
Caught #ScienceInAction for the first time in ages. Really good discussion on rabies in South Africa but the one that really caught my attention was @peaseroland.bsky.social discussion on earthquake risks
https://www.bbc.co.uk/sounds/play/w3ct5vd4?partner=uk.co.bbc&origin=share-mobile
'The drip, drip of casual racism, edgelord bigotry, bad-faith polemics, dog whistles, crass disinformation, dodgy pornbots, cynical grifting, tin-hat conspiracies and tiresome crypto bollocks became too much for some users of the site formerly known as Twitter fairly soon after Musk bought it in October 2022, later changing its name to X. '
https://www.ft.com/content/3edd3caf-05f5-4e65-a8ba-f86481ddc0e9
Thiago Carvalho
boosted
It's simple, Prime Minister: X is for people who think that Britain is about to lock up everyone who isn't woke, Bluesky is for people who think that sounds like a terrific idea, and Threads is for people who have no idea what either of the others are on about.
Truth Social is for people who think they run the Internet, Nostr is for people who think they should run the internet, and Mastodon is for people who actually do run the Internet.
& 4Chan people don’t care as long as they have big tits.
'She didn’t find out what it meant until September of that year, when patients with similar symptoms started to come to a university hospital in Yenagoa, the capital of Bayelsa state, a 3-hour drive west of Port Harcourt. Many were young men with genital lesions, and many also had HIV. Ultimately, tests revealed those patients had monkeypox, a viral disease that had only been documented in Nigeria three times, with the last case occurring 39 years earlier.'
Thiago Carvalho
boosted
Breakthrough Infections after Postexposure Vaccination against Mpox
As for any vaccine, infection is always possible (antibody waning, pathogen mutating). Infection is NOT disease.
Thiago Carvalho
boosted
We need good PSAs
Thank you to Yale for publishing a wonderful handout with great graphics for the general public. This is one about asymptomatic infections that should be posted everywhere. https://pdflink.to/yale-covid-19-immune-system-impacts/. Please share with friends, family, work, school, church and social circles. #CovidIsNotOver #MaskUp #Covid #Covid19
Thiago Carvalho
boosted
Hospitals in India hit as doctors begin nationwide strike over trainee’s rape and murder | India | The Guardian
https://www.theguardian.com/world/article/2024/aug/17/hospitals-in-india-hit-as-doctors-begin-nationwide-strike-over-trainees-and
'Taken together, our results show that cellular energy regulates the effect of codon optimality on mRNA stability. Codon optimality matters more in conditions of scarcer energy, such as tissues with low mitochondrial activity, older age, oxygen deprivation, or exposure to specific drugs'
https://www.embopress.org/doi/full/10.1038/s44320-024-00026-9
Thiago Carvalho
boosted
'Now, a handful of health care companies are preparing to introduce a new model for cervical cancer screening and prevention that would circumvent the speculum: self-collection, in which a woman swabs her vagina in the doctor’s office, using only a narrow swab that looks similar to the one used during a Covid test. Once the sample is collected, a lab would test it for the strains of human papillomavirus, or HPV, most likely to cause cervical cancer.'
https://www.nytimes.com/2024/08/15/well/pap-smear-cervical-cancer-test-alternative.html
Thiago Carvalho
boosted
'Swiss drugmaker Roche turned down a potential $14bn-a-year weight-loss pill now being developed by rival Eli Lilly that could have given it a leading position in the booming weight-loss market, according to company filings and people close to discussions.'
https://www.ft.com/content/78057a2c-60b8-410f-8731-b7c787991a57
I've worked on all of science, from B cells to T cells.
https://fellowsherpa.com
Joined Nov 2022
