An interesting problem with immortality is that it would be very difficult to remain conscious forever. Like driving the car, everything would eventually become automatic, and you'd gradually zone out and go on autopilot. Nothing is unexpected if you live long enough.
@BartoszMilewski - In his novel "Permutation City", Egan has some characters deal with this by having an 'exoself' that occasionally steps in and sets new psychological parameters to keep things interesting. Even this could get boring *eventually*, but it's an interesting idea. For example one character decides to make themselves fascinated by carpentry until they can reliably craft wonderful furniture. Then the exoself steps in and the character switches to entomology. There is still an odor of futility here.
@johncarlosbaez@BartoszMilewski Diaspora, and then Incandescence, had an interpersonal take on this: What if the life itself is so successful that it is possible to collectively exhaust all the interesting bits galaxy-wide?