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About 10% of hypothyroid patients have reduced quality of life despite normal TSH concentration under therapy with levothyroxine (L-T4). A new randomised, double-blind trial demonstrated better QoL under L-T4 + L-T3 compared to L-T4 alone.

pubmed.ncbi.nlm.nih.gov/398652

doi.org/10.1186/s12902-025-018

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