Johannes W. Dietrich @drjwdietrich@qoto.org
- Sektion DES / Klinik
- http://www.endokrinologie.org
PD Dr. med. Johannes Dietrich, endocrinologist, head of the diabetes, endocrinology and metabolism section of #KKB @RUBMedizin. Views are my own.
Joined Nov 2022
Assessing diagnostic tools in #endocrinology with computer simulations https://link.medium.com/qDCugbiYZMb
Einladung zur 2. Endokrinologischen Abendsprechstunde "Up-to-date Schilddrüse 2024" am 25. September 2024.
#Schilddrüse #Nebenschilddrüse #Hypothyreose #Schilddrüsenchirurgie #Syndrom_T #SORSHOT
http://www.endokrinologie.org/resources/flyer-up-to-date-schilddruse-2024.pdf
#Metformin is a useful antidiabetic substance, but also an endocrine disruptor. A recent study shows that it reduces the set point of #thyroid homeostasis, but this effect is mitigated by #vitamin_D deficiency.
https://pubmed.ncbi.nlm.nih.gov/39204438/
https://doi.org/10.3390/pharmaceutics16081093
Which programming language is fit for high-performance computer simulations in biomedical #cybernetics? We found that #Free_Pascal generates faster code than S/R and #Python. Interestingly, Object #Pascal even outperforms #Swift and C++.
https://doi.org/10.14201/adcaij.31762
https://revistas.usal.es/cinco/index.php/2255-2863/article/view/31762
Both sensorimotor and autonomic #neuropathy may be common in #hypothyroidism, despite treatment.
#Inflammation plays a key role in the pathogenesis of #diabetes mellitus. In our newest paper, we show that treatment of #hidradenitis_suppurativa (#acne_inversa) may cause remission of diabetes. CN: medical images in full text. https://pubmed.ncbi.nlm.nih.gov/39106221/ https://doi.org/10.1111/ddg.15490
Die Grafen von #Neuburg-#Falkenstein waren ein bedeutendes Adelsgeschlecht der #Stauferzeit. Ihr Gebiet reichte von Oberbayern bis Südtirol und Niederösterreich. Ihre Stammburg #Unterfalkenstein wurde bei dem bayerischen #Hochwasser schwer beschädigt. #Klima
Sensorimotor #polyneuropathy may be common in treated autoimmune thyroiditis, but, unlike in other causes of #neuropathy (e. g. #diabetes), it has a unique pattern in quantitative sensory testing (#QST) with low thresholds for mechanical and thermal pain.
Should we, therefore, classify #syndrome_T as a psychosomatic disease? This would be premature and probably wrong. We found signs of sensorimotor and autonomic #neuropathy that depend on autoimmunity and #thyroid's secretory capacity (#SPINA_GT).
Our newest paper provides new insights into the conundrum of #syndrome_T / #sorshot. #Anxiety and #depression are significantly more common in autoimmune #thyroiditis compared to healthy controls.
Stellenausschreibung für Medizinische Fachangestellte in der Sektion #Diabetologie, #Endokrinologie und #Stoffwechsel am KKB / UK RUB @RUBMedizin.
Wir freuen und auf Ihre Bewerbung!
Telefonsprechstunde zu Schilddrüsenerkrankungen
Zum Weltschilddrüsentag am 25. Mai bietet das Schilddrüsenzentrum Bochum eine spezielle Telefonsprechstunde an, die allen Interessierten und Betroffenen offensteht:
Samstag, 25. Mai, von 11:00 bis 14:00 Uhr unter der Rufnummer (0234) 509-6095
Die Deutsche Gesellschaft für #Kybernetik, Informations- und #Systemtheorie hat Peter K. Fleissner und mir den Heinz von Foerster-Preis verliehen.
Ich danke meinen Lehrer:innen und Kooperationspartner:innen, die meine Arbeit im Laufe der letzten 30 Jahre möglich gemacht haben.
Einladung zur Jahrestagung der Deutschen Gesellschaft für #Kybernetik im Rahmen der Jahrestagung der Leibniz-Sozietät in Berlin. Es erfolgt eine parallele Life-Übertragung online:
Sadly, John Midgley, a pioneer in #thyroid diagnostics and co-author of multiple papers by our group, passed away. Read Rudolf Hoermann's obituary at The Guardian:
https://www.theguardian.com/society/2024/apr/02/john-midgley-obituary
Johannes W. Dietrich
boosted
#SPINA_GT, #SPINA_GD and Jostel's TSH index (#JTI or #TSHI) are predictors of survival in patients with #Takotsubo syndrome (#stress #cardiomyopathy), as recently demonstrated in the international GEIST registry.
https://pubmed.ncbi.nlm.nih.gov/38502972/
https://doi.org/10.1016/j.ebiom.2024.105063
Our newest paper has been published. Based on machine learning with k-medoids #clustering we identified three different signatures of #thyroid #homeostasis that predict the prognosis of patients with #Takotsubo syndrome.
https://pubmed.ncbi.nlm.nih.gov/38502972/
https://doi.org/10.1016/j.ebiom.2024.105063
Therefore, the non-increased and, in many cases, even reduced beta cell function in metabolic syndrome may not mirror an "either-or" question but be part of continuous evolution. It may be a source of prediabetes and diabetes but also prevent insulinoma.
The answer to this question may be in glucose toxicity leading to a biphasic response, thereby preventing neoplastic effects of dynamical compensation by mutant takeover.
- Sektion DES / Klinik
- http://www.endokrinologie.org
PD Dr. med. Johannes Dietrich, endocrinologist, head of the diabetes, endocrinology and metabolism section of #KKB @RUBMedizin. Views are my own.
Joined Nov 2022
