Technically we still have a chief of staff, he doesn't step down until jan 1st, at which point he may already have a replacement lined up. Also we most absolutely have an attorney general, Jeff sessions stepped down and was replaced by Matt Whitaker.

With that said despite the misleading and inaccurate statements in this meme it does convey a very valid point, that being, trump is a terrible leader and does not take the advice of others. He thinks he knows it all while knowing nothing and this arrogance combined with stupidity is the disease and everyone resigning is the symptom