@gorskon Good write up. As I've argued on my blog, I think the ultimate source of the problem is Nullism - the belief that the scientific method mandates that you have a Null Hypothesis that wins by default, until/unless it is disproven. EBM then ramps up the default thinking to 11. OTOH, if you don't let a hypothesis win by default, but instead carefully weigh all evidence for and against, then there would be no role for an evidence pyramid.