Gaspar Jekely @jekely@qoto.org
- Platynereis connectome
- https://catmaid.jekelylab.ex.ac.uk
Professor at Centre for Organismal Studies (COS), University of Heidelberg, Germany
and
Living Systems Institute (LSI), University of Exeter, UK.
#neuroscience of marine larvae, #connectomics, #cilia, ciliary swimming, cell and nervous system #evolution, #GPCR, #neuropeptides, #Platynereis, #Trichoplax, #Nematostella, #Schistosoma, #coral #neuroscience #rstat #evolution
Joined Nov 2022
Gaspar Jekely
boosted
#introduction
Hi everyone,
I am Nila. I am a neuroscientist & currently a Postdoc in Rainer Friedrich's lab at FMI. I study the circuit of the olfactory bulb in the adult zebrafish using a connectomic approach. Recently I have been a bit sidetracked by telencephalic temptations...
I am here to keep up to date and exchange with the scientific community. But I love to have my mind blown by anything nature. So, I am hoping to learn many fun facts outside of my horizons (& to see many beautiful images as well).
I am a first-gen academic which has sometimes been a struggle (mostly in my mind). Topics of open access, social mobility & justice are important to me, and I do have to learn a lot there.
Parenting 3 little humans doesn't leave much energy for hobbies but running is my lifeline.
Gaspar Jekely
boosted
#introduction (2).
I am a neurophysiologist interested in decision-making systems constituted of small number of neurons, whose functional/synaptic properties and individual involvement in genesis of a behavior are identified.
Hopefully, I will be able to share some science soon.
#Aplysia #neuroscience #learning & #memory #epigenetics #plasticity #neuromodulation
Alternatively, if you have experience in electron microscopy or image analysis and are interested in volume EM, you can join our #volumeEM projects either to do EM or work on the data analysis side of volume EM and connectomics projects
5/5
There will be new #postdoc and #PhD openings, if you are interested to work with us, please get in touch. Possible topics include #Platynereis neurobiology, eye #evolution, #connectomics, the behaviour of ciliated #larvae etc. You can work on a growing selection of organisms kept in the lab, including Platynereis (still our no. 1), #Trichoplax, #Nematostella or join more exotic projects investigating hard-to-culture marine animals including polyclads, hemichordates or amphioxus.
4/5
We am very excited to move to COS and join its vibrant community. We have a shared interest in the study of organismal biology across the boundaries of biological levels of organization.
3/5
We will build up a new department on Evolutionary Neurobiology with a focus on marine larval behaviour, comparative #connectomics, molecular organismal biology, #neuromodulation and related topics.
#neuroscience #evolution
2/5
I am very happy to announce that our lab will soon move to the University of #Heidelberg to join the Centre for Organismal Studies (COS)
https://www.cos.uni-heidelberg.de/en
#COS
1/5
Great paper by Laura Piovani on high-quality cell atlases of oyster and polyclad flatworm larvae. Interesting new insights into cell-type diversity, young and old cell-types and evolution. Shell gland transcriptomes make oyster larvae look young. It was a pleasure to collaborate with Telford Lab et al. on this project. https://www.biorxiv.org/content/10.1101/2023.01.04.522730v1
Gaspar Jekely
boosted
Our latest work on cell type diversity in Squid / #Cephalopods
is now out out in eLife:
https://elifesciences.org/articles/80670#content
Cephalopods are a unique group of animals. They
have independently evolved advanced cognitive abilities and strikingly complex brains, in many aspects not unlike mammals.
However still little is known about the organisation of their brains and cell types it contains.
Gaspar Jekely
boosted
I've just published my first ever blog: "The Tragedy of the Non-Commons"
I wrote it in July, frustrated by a Twitter thread about how the Tragedy of the #Commons continues to be taught at universities. I then left it (it's somewhat experiemental) but with #COP27 and #Twittermigration coinciding this week, I just wanted it to be out there. Would love for it to be shared here on our #digitalcommons and grateful for any comments
https://medium.com/@p.vonhellermann/the-tragedy-of-the-non-commons-4bfad884cdbe
Gaspar Jekely
boosted
Wanted to share our recent paper on how a cell, Chlamydomonas, "knows" when its flagella are removed. When flagella are detached in this unicellular alga, they grow back in an hour, and while that happens a whole program of genes are turned on. Here we show that induction depends on intraflagellar transport, suggesting a model in which a repressor is sequestered in flagella when they are re-growing, and then accumulates to turn genes off as growth tapers off.
https://www.molbiolcell.org/doi/10.1091/mbc.E22-09-0444
Gaspar Jekely
boosted
Elsevier appears to be collecting and monetizing our personal data, sometimes without our consent. The data they collect can be used to "extrapolate core working hours, vacation times, and other patterns of a person’s life."
What can we do?
Over 20,000 researchers are refusing to publish, review, or edit for Elsevier. You can also ask them to delete your "non-integral" personal data: https://www.elsevier.com/legal/privacy-policy/data-request
Article by @eikofried https://eiko-fried.com/welcome-to-hotel-elsevier-you-can-check-out-any-time-you-like-not/?=IwAR3DJSxwVn4OQB_HcRr8uNS1szepCAWy_9wbJo3Hi_ZcfdBN-trs6ndgmJo
#OpenScience @academicchatter
Application for participation now open for the Janelia "Neuropeptide Signaling: Bridging Cell Biology, Neurophysiology, and Behavior" #meeting in April 16 - 19, 2023.
Deadline: Jan 18
https://www.janelia.org/you-janelia/conferences/neuropeptide-signaling-bridging-cell-biology-neurophysiology-and-behavior
#Neuropeptide #Neurophysiology #Neuroscience
Gaspar Jekely
boosted
Excited to share our new manuscript on a novel #neuropeptide family that regulates #feeding across #evolution. Kudos to #Pat_TFrancisco for tackling this challenging project and coming up with the name #marmite. #homeostasis https://www.biorxiv.org/content/10.1101/2022.12.12.520095v3 Still figuring this space out. In the meantime if you want to check out the thread on the competing platform (links to the competition are allowed here?). https://twitter.com/RibeiroCarlitos/status/1605147211918196736 #drosophila
Gaspar Jekely
boosted
The website for ICIV 2023 hosted by the Lund Vision Group is online at: https://iciv.se
July 27 to August 3 in 2023 – at Bäckaskog Castle, Sweden.
Abstract submission will open January 1. Mark your calendars!
Gaspar Jekely
boosted
Hello world!
I have been studying cilia since 2005, been modestly active on Twitter since 2014 and will be posting about anything related to #cilia, #signaling, #BardetBiedlSyndrome
In this paper we generated most of the figures entirely in R for open science and reproducibility. All code is shared here:
https://github.com/JekelyLab/Jasek_et_al
The figures and analyses can be regenerated by the code that will query our public #CATMAID database where all EM data, tracings and annotations are shared:
https://catmaid.jekelylab.ex.ac.uk (project id: 11)
#openscience #rstat
We also mapped #motoneuron synapses to the desmosomal connectome to infer the extent of tissue influenced by motoneurons. We suggest that such cellular-level maps based on #volumeEM data and the integrative analysis of synaptic and adherent force networks will be important to elucidate body mechanics and the nervous control of movement.
The #endoskeleton formed by the #aciculae and supported by many muscles is quite unique to polychaete annelids and represents the only example outside the #tetrapods of animals with a trunk appendages rigidified by an endoskeleton. Aciculae evolved in stem errant #annelids in the Early #Ordovician indicating the deep ancestry of these structures, predating tetrapod limbs.
We analysed the network in many different ways and found that its structure is quite different from the synaptic #connectome and random networks. One of the interesting findings was that the #aciculae - chitin rods that form an #endoskeleton in the segmental #appendages - are highly connected hubs in the #network and a large number of #muscles is involved in moving them.
- Platynereis connectome
- https://catmaid.jekelylab.ex.ac.uk
Professor at Centre for Organismal Studies (COS), University of Heidelberg, Germany
and
Living Systems Institute (LSI), University of Exeter, UK.
#neuroscience of marine larvae, #connectomics, #cilia, ciliary swimming, cell and nervous system #evolution, #GPCR, #neuropeptides, #Platynereis, #Trichoplax, #Nematostella, #Schistosoma, #coral #neuroscience #rstat #evolution
Joined Nov 2022
