jonmoulton @jonmoulton@qoto.org

Integrative genetic analysis illuminates ALS heritability and identifies risk genes. https://www.nature.com/articles/s41467-022-35724-1 #Morpholino

Structural remodeling of AAA+ ATPase p97 by adaptor protein ASPL facilitates posttranslational methylation by METTL21D. https://www.pnas.org/doi/10.1073/pnas.2208941120 #Morpholino

Morpholino-Mediated Exons 28-29 Skipping of Dysferlin and Characterization of Multiexon-skipped Dysferlin using RT-PCR, Immunoblotting, and Membrane Wounding Assay. https://link.springer.com/protocol/10.1007/978-1-0716-2772-3_11 #Morpholino

Unraveling Presenilin 2 Functions in a Knockout Zebrafish Line to Shed Light into Alzheimer’s Disease Pathogenesis. https://www.mdpi.com/2073-4409/12/3/376/htm #Morpholino

SMIM36, a novel and conserved microprotein, is involved in retinal lamination in zebrafish. https://www.biorxiv.org/content/10.1101/2023.01.14.524032v1 #Morpholino

Multiple pkd and piezo gene family members are required for atrioventricular valve formation. https://www.nature.com/articles/s41467-023-35843-3 #Morpholino

Identification of the Time Period during Which BMP Signaling Regulates Proliferation of Neural Progenitor Cells in Zebrafish. https://www.mdpi.com/1422-0067/24/2/1733 #Morpholino

Endothelial cells require functional FLVCR1a during developmental and adult angiogenesis. https://link.springer.com/article/10.1007/s10456-023-09865-w #Morpholino

Inducible in vivo genome editing in the sea star Patiria miniata. https://www.biorxiv.org/content/10.1101/2023.01.09.523328v1 #Morpholino

Channel Function of Polycystin-2 in the Endoplasmic Reticulum Protects against Autosomal Dominant Polycystic Kidney Disease. https://journals.lww.com/jasn/Abstract/2022/08000/Channel_Function_of_Polycystin_2_in_the.13.aspx #Morpholino

Somitic mesoderm morphogenesis is necessary for neural tube closure during Xenopus development. https://www.frontiersin.org/articles/10.3389/fcell.2022.1091629/full #Morpholino

Repeat-associated non-AUG translation induces cytoplasmic aggregation of CAG repeat-containing RNAs. https://www.pnas.org/doi/abs/10.1073/pnas.2215071120 #Morpholino

Hydrozoan sperm-specific SPKK motif-containing histone H2B variants stabilise chromatin with limited compaction. https://journals.biologists.com/dev/article/150/1/dev201058/286546/Hydrozoan-sperm-specific-SPKK-motif-containing #Morpholino

C5-pyrimidine-functionalized morpholino oligonucleotides exhibit differential binding affinity, target specificity and lipophilicity. https://pubs.rsc.org/en/content/articlelanding/2023/OB/D2OB01759H #Morpholino

Establishment of quantitative and consistent in vitro skeletal muscle pathological models of myotonic dystrophy type 1 using patient-derived iPSCs. https://www.nature.com/articles/s41598-022-26614-z #Morpholino

maea affects head formation through ß-catenin degradation during early Xenopus laevis development. https://onlinelibrary.wiley.com/doi/10.1111/dgd.12828 #Morpholino

Distinct biogenesis pathways may have led to functional divergence of the human and Drosophila Arglu1 sisRNA. https://www.embopress.org/doi/abs/10.15252/embr.202154350 #Morpholino

SCGN deficiency is a risk factor for autism spectrum disorder. https://www.nature.com/articles/s41392-022-01225-2 #Morpholino

Targeting G-quadruplex for rescuing impaired chondrogenesis in WRN-deficient stem cells. https://cellandbioscience.biomedcentral.com/articles/10.1186/s13578-022-00939-8 #Morpholino

Characterization of the innate immune response to Streptococcus pneumoniae infection in zebrafish. https://journals.plos.org/plosgenetics/article?id=10.1371/journal.pgen.1010586
#Morpholino