jonmoulton @jonmoulton@qoto.org

Blood flow regulates acvrl1 transcription via ligand-dependent Alk1 activity. https://doi.org/10.1101/2024.01.25.576046 #Morpholino

Systemic delivery of a splice-switching oligonucleotide heteroduplex corrects splicing in central nervous system and muscle in spinal muscular atrophy mice. https://www.biorxiv.org/content/10.1101/2024.01.24.577012v1 #Morpholino

Perturbed development of calb2b expressing dI6 interneurons and motor neurons underlies locomotor defects observed in calretinin knock-down zebrafish larvae. https://www.sciencedirect.com/science/article/pii/S0012160624000010 #Morpholino

An anti-sense oligonucleotide efficiently suppresses splicing of an alternative exon in vascular smooth muscle in vivo. https://journals.physiology.org/doi/abs/10.1152/ajpheart.00745.2023 Vivo-#Morpholino

Moderate Elevation of Homocysteine Induces Endothelial Dysfunction through Adaptive UPR Activation and Metabolic Rewiring. https://www.mdpi.com/2073-4409/13/3/214 #Morpholino

TUBA4A downregulation as observed in ALS post-mortem motor cortex causes ALS-related abnormalities in zebrafish. https://www.frontiersin.org/articles/10.3389/fncel.2024.1340240/abstract #Morpholino

Deficiency of copper responsive gene stmn4 induces retinal developmental defects. https://link.springer.com/article/10.1007/s10565-024-09847-8 #Morpholino

The Effect of Morpholino Oligonucleotides to Gene Anxa2a on the Embryonic Development of Danio rerio. https://link.springer.com/article/10.3103/S0891416823030059 #Morpholino

When I tweet #Morpholino citations, they are also going into our searchable online database. You can access citations & abstracts of over 12,000 papers at pubs.gene-tools.com

Epileptic phenotypes in slc13a5 loss-of-function zebrafish are rescued by blocking NMDA receptor signaling. https://www.biorxiv.org/content/10.1101/2024.01.15.575806v1 #Morpholino

Endogenous biosynthesis of docosahexaenoic acid (DHA) regulates fish oocyte maturation by promoting pregnenolone production. https://www.zoores.ac.cn/article/doi/10.24272/j.issn.2095-8137.2023.032 #Morpholino

Ciliary length regulation by intraflagellar transport in zebrafish. https://www.biorxiv.org/content/10.1101/2024.01.16.575975v1 #Morpholino

Dyrk1a is required for craniofacial development in Xenopus laevis. https://www.biorxiv.org/content/10.1101/2024.01.13.575394v1 #Morpholino

Characterizing CSNK2A1 Mutant-Induced Morphological Phenotypes in Zebrafish (Danio rerio): Insights into Okur-Chung Neurodevelopmental Syndrome (OCNDS). https://www.biorxiv.org/content/10.1101/2024.01.09.574075v1 #Morpholino

Adhesion-induced cortical flows pattern E-cadherin-mediated cell contacts. https://www.sciencedirect.com/science/article/pii/S096098222301655X #Morpholino

amer1 Regulates Zebrafish Craniofacial Development by Interacting with the Wnt/β-Catenin Pathway. https://www.mdpi.com/1422-0067/25/2/734 #Morpholino

Variants in the WDR44 WD40-repeat domain cause a spectrum of ciliopathy by impairing ciliogenesis initiation. https://www.nature.com/articles/s41467-023-44611-2 #Morpholino

Antagonistic interactions safeguard mitotic propagation of genetic and epigenetic information in zebrafish. https://www.nature.com/articles/s42003-023-05692-3 #Morpholino

Macrophages inhibit extracellular hyphal growth of A. fumigatus through Rac2 GTPase signaling. https://journals.asm.org/doi/10.1128/iai.00380-23 #Morpholino

Piezo1-dependent regulation of pericyte proliferation by blood flow during brain vascular development. https://www.cell.com/cell-reports/fulltext/S2211-1247(23)01663-7 #Morpholino