Maternal mRNA deadenylation and allocation via Rbm14 condensates facilitate vertebrate blastula development. https://www.embopress.org/doi/abs/10.15252/embj.2022111364 #Morpholino
Chemokine signaling synchronizes angioblast proliferation and differentiation during pharyngeal arch artery vasculogenesis. https://journals.biologists.com/dev/article/149/23/dev200754/285824/Chemokine-signaling-synchronizes-angioblast #Morpholino
Regenerative failure of intrahepatic biliary cells in Alagille syndrome rescued by elevated Jagged/Notch/Sox9 signaling. https://www.pnas.org/doi/10.1073/pnas.2201097119 #Morpholino
A Missense Variant in PDK1 Associated with Severe Neurodevelopmental Delay and Epilepsy. https://www.mdpi.com/2227-9059/10/12/3171 #Morpholino
CD14+/CD31+ Monocytes Expanded by UM171 Correct Hemophilia A in Zebrafish upon Lentiviral Gene Transfer of Factor VIII . https://ashpublications.org/bloodadvances/article/doi/10.1182/bloodadvances.2022009014/493421/CD14-CD31-Monocytes-Expanded-by-UM171-Correct #Morpholino
Vegf signaling between Müller glia and vascular endothelial cells is regulated by immune cells and stimulates retina regeneration. https://www.pnas.org/doi/10.1073/pnas.2211690119 #Morpholino
Human SLFN5 and its Xenopus Laevis ortholog regulate entry into mitosis and oocyte meiotic resumption. https://www.nature.com/articles/s41420-022-01274-0 #Morpholino
Temporal changes in plasma membrane lipid content induce endocytosis to regulate developmental epithelial-to-mesenchymal transition. https://www.pnas.org/doi/10.1073/pnas.2212879119 #Morpholino
Ckb and Ybx2 interact with Ribc2 and are necessary for the ciliary beating of multi-cilia. https://link.springer.com/article/10.1007/s13258-022-01350-w #Morpholino
Loxhd1b inhibits the hair cell development in zebrafish: Possible relation to the BDNF/TrkB/ERK pathway. https://www.frontiersin.org/articles/10.3389/fncel.2022.1065309/full #Morpholino
ftr82 is necessary for hair cell morphogenesis and auditory function during zebrafish development. https://www.sciencedirect.com/science/article/abs/pii/S1673852722002521 #Morpholino
PPMOs: A Case Study for Cell-Penetrating Peptide Application. https://onlinelibrary.wiley.com/doi/10.1002/9783527835997.ch15 #Morpholino
LOF variants identifying candidate genes of laterality defects patients with congenital heart disease. https://journals.plos.org/plosgenetics/article?id=10.1371/journal.pgen.1010530 #Morpholino
Synapsin III Regulates Dopaminergic Neuron Development in Vertebrates. https://www.mdpi.com/2073-4409/11/23/3902 #Morpholino
Transposable elements drive the evolution of metazoan zinc finger genes. https://www.biorxiv.org/content/10.1101/2022.11.29.518450v1 #Morpholino
Parental mutations influence wild-type offspring via transcriptional adaptation. https://www.science.org/doi/10.1126/sciadv.abj2029 #Morpholino
Top2a promotes the development of social behavior via PRC2 and H3K27me3. https://www.science.org/doi/pdf/10.1126/sciadv.abm7069 #Morpholino
Chromosome segregation fidelity requires microtubule polyglutamylation by the cancer downregulated enzyme TTLL11. https://www.nature.com/articles/s41467-022-34909-y #Morpholino
Microenvironmental Snail1 is a driver of immunosuppression in melanoma. https://www.biorxiv.org/content/10.1101/2022.11.23.517623v1 Vivo-#Morpholino
N-Fluoroalkylated Morpholinos – a New Class of Nucleoside Analogues. https://chemistry-europe.onlinelibrary.wiley.com/doi/10.1002/chem.202203248 #Morpholino
It's been all Morpholinos all the time for about 23 years. I'm a scientist with Gene Tools LLC.