jonmoulton @jonmoulton@qoto.org

SCGN deficiency is a risk factor for autism spectrum disorder. https://www.nature.com/articles/s41392-022-01225-2 #Morpholino

Targeting G-quadruplex for rescuing impaired chondrogenesis in WRN-deficient stem cells. https://cellandbioscience.biomedcentral.com/articles/10.1186/s13578-022-00939-8 #Morpholino

Characterization of the innate immune response to Streptococcus pneumoniae infection in zebrafish. https://journals.plos.org/plosgenetics/article?id=10.1371/journal.pgen.1010586
#Morpholino

α-1,6-Fucosyltransferase Is Essential for Myogenesis in Zebrafish. https://www.mdpi.com/2073-4409/12/1/144 #Morpholino

The Male-Biased Expression of miR-2954 Is Involved in the Male Pathway of Chicken Sex Differentiation. https://www.mdpi.com/2073-4409/12/1/4 Vivo-#Morpholino

Identification of the genes encoding candidate septate junction components expressed during early development of the sea urchin, Strongylocentrotus purpuratus, and evidence of a role for Mesh in the formation of the gut barrier.
https://www.sciencedirect.com/science/article/abs/pii/S0012160622002366 Vivo-#Morpholino

Ste20-like kinase activity promotes meiotic resumption and spindle microtubule stability in mouse oocytes. https://onlinelibrary.wiley.com/doi/10.1111/cpr.13391 #Morpholino

Kindlin2 enables EphB/ephrinB bi-directional signaling to support vascular development. https://www.life-science-alliance.org/content/6/3/e202201800 #Morpholino

Nuclear-cytoplasmic compartmentalization of cyclin B1-Cdk1 promotes robust timing of mitotic events. https://www.sciencedirect.com/science/article/pii/S2211124722017661 #Morpholino

Lasp1 Expression Is Implicated in Embryonic Development of Zebrafish. https://www.mdpi.com/2073-4425/14/1/35 #Morpholino

Functional screening of congenital heart disease risk loci identifies 5 genes essential for heart development in zebrafish.
https://link.springer.com/article/10.1007/s00018-022-04669-5 #Morpholino

Phosphorylation of adducin-1 by TPX2 promotes interpolar microtubule homeostasis and precise chromosome segregation in mouse oocytes. https://cellandbioscience.biomedcentral.com/articles/10.1186/s13578-022-00943-y #Morpholino

Evaluation of Cardiovascular Toxicity of Folic Acid and 6S-5-Methyltetrahydrofolate-Calcium in Early Embryonic Development. https://www.mdpi.com/2073-4409/11/24/3946 #Morpholino

Synthesis of 5′-Thiol Functionalized Morpholino Oligo-Nucleotide and Subsequent Conjugation with IGT to Improve Delivery and Antisense Efficacy In Vitro. https://pubs.acs.org/doi/10.1021/acs.bioconjchem.2c00587 #Morpholino

Evi5 is required for Xenopus limb and tail regeneration. https://www.frontiersin.org/articles/10.3389/fcell.2022.1027666/full #Morpholino

The Splicing Factor PTBP1 Represses TP63 γ Isoform Production in Squamous Cell Carcinoma. https://aacrjournals.org/cancerrescommun/article/2/12/1669/711751/The-Splicing-Factor-PTBP1-Represses-TP63-Isoform #Morpholino

AUF-1 knockdown in mice undermines gut microbial butyrate-driven hypocholesterolemia through AUF-1–Dicer-1–mir-122 hierarchy. https://www.frontiersin.org/articles/10.3389/fcimb.2022.1011386/full #Morpholino

Brain endothelial cells acquire blood-brain barrier properties in the absence of Vegf-dependent CNS angiogenesis.
https://www.sciencedirect.com/science/article/pii/S0012160622002184 #Morpholino

Anp32a Promotes Neuronal Regeneration after Spinal Cord Injury of Zebrafish Embryos. https://www.mdpi.com/1422-0067/23/24/15921 #Morpholino

G-rich motifs within phosphorothioate-based antisense oligonucleotides (ASOs) drive activation of FXN expression through indirect effects. https://academic.oup.com/nar/advance-article/doi/10.1093/nar/gkac1108/6895196 #Morpholino