jonmoulton @jonmoulton@qoto.org

lmo4a Contributes to Zebrafish Inner Ear and Vestibular Development via Regulation of the Bmp Pathway. https://www.mdpi.com/2073-4425/14/7/1371 #Morpholino

Upf3a but not Upf1 mediates the genetic compensation response induced by leg1 deleterious mutations in an H3K4me3-independent manner. https://www.nature.com/articles/s41421-023-00550-2 #Morpholino

Deep intronic founder mutations identified in the ERCC4/XPF gene are potential therapeutic targets for a high-frequency form of xeroderma pigmentosum. https://www.pnas.org/doi/10.1073/pnas.2217423120 #Morpholino

Synthesis and Biophysical Studies of High Affinity #Morpholino Oligomers Containing G-clamp Analogs. https://chemrxiv.org/engage/chemrxiv/article-details/649ae6c1ba3e99daef1f7404

Identification of protein phosphatase 4 catalytic subunit as a Wnt promoting factor in pan-cancer and Xenopus early embryogenesis. https://www.nature.com/articles/s41598-023-35719-y #Morpholino

Styxl2 regulates de novo sarcomere assembly by binding to non-muscle myosin IIs and promoting their degradation. https://elifesciences.org/reviewed-preprints/87434 #Morpholino

UBAP2 plays a role in bone homeostasis through the regulation of osteoblastogenesis and osteoclastogenesis. https://www.nature.com/articles/s41467-023-39448-8 #Morpholino

Patent
Morpholino oligonucleotides useful in cancer treatment
https://patents.google.com/patent/US11679121B2/en
Includes delivery of #Morpholinos by irradiation

Transmembrane protein 150b attenuates BMP signaling in the Xenopus organizer. https://onlinelibrary.wiley.com/doi/10.1002/jcp.31059 #Morpholino

The Crucial Role of CTCF in Mitotic Progression during Early Development of Sea Urchin. https://onlinelibrary.wiley.com/doi/10.1111/dgd.12875 #Morpholino

Defective neurite elongation and branching in Nibp/Trappc9 deficient zebrafish and mice. https://www.ijbs.com/v19p3226.htm #Morpholino

Sfxn5 Regulation of Actin Polymerization for Neutrophil Spreading Depends on a Citrate-Cholesterol-PI(4,5)P2 Pathway. https://journals.aai.org/jimmunol/article-abstract/doi/10.4049/jimmunol.2200863/265709/Sfxn5-Regulation-of-Actin-Polymerization-for
#Morpholino

Cell competition for neuron-derived trophic factor controls the turnover and lifespan of microglia. https://www.science.org/doi/10.1126/sciadv.adf9790 #Morpholino

ADAM11 a novel regulator of Wnt and BMP4 signaling in neural crest and cancer. https://www.biorxiv.org/content/10.1101/2023.06.13.544797v1 #Morpholino

Heme-deficient primitive red blood cells induce HSPC ferroptosis by altering iron homeostasis during zebrafish embryogenesis. https://journals.biologists.com/dev/article/150/20/dev201690/316750/Heme-deficient-primitive-red-blood-cells-induce #Morpholino

Loss of TDP-43 causes ectopic endothelial sprouting and migration defects through increased fibronectin, vcam 1 and integrin α4/β1. https://www.frontiersin.org/articles/10.3389/fcell.2023.1169962/full #Morpholino

SMARCAD1 and TOPBP1 contribute to heterochromatin maintenance at the transition from the 2C-like to the pluripotent state. https://elifesciences.org/reviewed-preprints/87742 #Morpholino

SMARCAD1 and TOPBP1 contribute to heterochromatin maintenance at the transition from the 2C-like to the pluripotent state. https://elifesciences.org/reviewed-preprints/87742 #Morpholino

A spatiotemporal barrier formed by Follistatin is required for left-right patterning. https://www.pnas.org/doi/10.1073/pnas.2219649120 #Morpholino

Fusobacterium nucleatum dissemination by neutrophils. https://www.tandfonline.com/doi/full/10.1080/20002297.2023.2217067 #Morpholino