jonmoulton @jonmoulton@qoto.org

Llgl1 mediates timely epicardial emergence and establishment of an apical laminin sheath around the trabeculating cardiac ventricle. https://www.biorxiv.org/content/10.1101/2023.08.14.553249v1 #Morpholino

Lymphocyte pathway analysis using naturally lymphocyte-deficient fish. https://onlinelibrary.wiley.com/doi/pdf/10.1002/eji.202350577 #Morpholino

Alternative splicing of its 5’-UTR limits CD20 mRNA translation and enables resistance to CD20-directed immunotherapies. https://www.biorxiv.org/content/10.1101/2023.02.19.529123v3 #Morpholino

Sequence specificity defines the effectiveness of PPMOs targeting Pseudomonas aeruginosa. https://journals.asm.org/doi/10.1128/aac.00245-23 #Morpholino

Sphingolipid metabolism is spatially regulated in the developing embryo by SOXE genes. https://www.biorxiv.org/content/10.1101/2023.08.10.552770v1 #Morpholino

Sclerotome-derived vascular smooth muscle progenitors contribute to the haematopoietic stem cell specification niche. https://www.biorxiv.org/content/10.1101/2023.08.09.552695v1 #Morpholino

Tmed10 deficiency results in impaired exocrine pancreatic differentiation in zebrafish larvae. https://www.sciencedirect.com/science/article/abs/pii/S0012160623001422 #Morpholino

Protocol for constructing GQD-PMO functionalized FET-biosensor for ultrasensitive exosomal miRNA detection. https://www.sciencedirect.com/science/article/pii/S2666166723004835 #Morpholino

Maternal RNA binding protein with multiple splicing 2 (RBPMS2) is involved in mouse blastocyst formation through the bone morphogenetic protein pathway. https://www.rbmojournal.com/article/S1472-6483(23)00336-X/fulltext #Morpholino

Cfdp1 Is Essential for Cardiac Development and Function. https://www.mdpi.com/2073-4409/12/15/1994 #Morpholino

β-Amyloid targeting nanodrug for neuron-specific delivery of nucleic acids in Alzheimer's disease mouse models. https://www.sciencedirect.com/science/article/pii/S0168365923004972 #Morpholino

Matriptase-dependent epidermal pre-neoplasm in zebrafish embryos caused by a combination of hypotonic stress and epithelial polarity defects. https://journals.plos.org/plosgenetics/article?id=10.1371/journal.pgen.1010873 #Morpholino

#Morpholino blog from Biobide
https://blog.biobide.com/morpholino-and-zebrafish-benefits-and-applications

[Prickle planar cell polarity protein 1 involved in the pathogenesis of skeletal class Ⅲ malocclusion]. https://rs.yiigle.com/cmaid/1468270 #Morpholino

Deletion of miR-146a enhances therapeutic protein restoration in model of dystrophin exon skipping. https://www.biorxiv.org/content/10.1101/2023.05.09.540042v2 #Morpholino

Neuronal migration prevents spatial competition in retinal morphogenesis. https://www.nature.com/articles/s41586-023-06392-y #Morpholino

Unreprogrammed H3K9me3 prevents minor zygotic genome activation and lineage commitment in SCNT embryos. https://www.nature.com/articles/s41467-023-40496-3 #Morpholino

An integeative GWAS followed by functional investigation reveals possible involvement of CNTNAP5 in glaucomatous neurodegeneration. https://onlinelibrary.wiley.com/doi/full/10.1111/jnc.15896 #Morpholino

Ribo-On and Ribo-Off tools using a self-cleaving ribozyme allow manipulation of endogenous gene expression in C. elegans. https://www.nature.com/articles/s42003-023-05184-4 Vivo-#Morpholino

The endosomal escape vehicle platform enhances delivery of oligonucleotides in preclinical models of neuromuscular disorders. https://www.cell.com/molecular-therapy-family/nucleic-acids/fulltext/S2162-2531(23)00172-5 #Morpholino