antipsychotic properties of cannabis compound CBD
"[CBD] inhibited the binding of radio-domperidone … in the same biphasic manner as a dopamine partial agonist #antipsychotic drug such as aripiprazole… the dopamine partial agonist action of cannabidiol may account for its clinical antipsychotic effects."
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5315552/
Schedule I drug in the USA, same as meth… unless you buy it in a pill called #Epidiolex.
#CBD #Cannabis #Meds #MedicalMarijuana #Schizophrenia #Bipolar #MentalHealth
antipsychotic properties of cannabis compound CBD
Another choice quote from the paper:
"[T]wo recent reports
showed that 800 to 1000 mg of cannabidiol per day alleviated the signs and symptoms of schizophrenia…"
So, a gram of 100% #CBD a day, probably at the absolute cheapest where I live might run like $20-25 a day? Not positive. Prices continue to fall, though. And that's not taking into account potential bioavailability hacks.
Can't wait to see what this can do for bipolar disorder.
antipsychotic properties of cannabis compound CBD
I just realized that this could explain the seemingly fantastical claim in my middle school health classes, based on ancient and dubious data, that smoking weed could lead to breast enlargement in men.
D2 antagonists or partial agonists can lead to gynecomastia as a side effect of the very action which produces their antipsychotic effect. Blocking D2 alters a feedback loop which regulates prolactin.
