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On day 4 of we want to share something we think everyone should know: there are no shortcuts in cognitive improvement.
You can read more about that and about our take on commercial neurotech here:

On day 3 of we would like to talk about scientific concepts we don't understand. No one gets it all, so we think it's important to acknowledge that.

For us, one of the biggest mysteries in neuroscience remains the free energy principle. Despite numerous attempts to read the scientific literature on the topic, as well as to listen to Karl Friston's talks, it seems that our brains refuse to minimize their uncertainty with respect to this.

What's something that you still don't really grasp in your field?

Link to post if you want to read more about this:

Day 2 of #ChemistryAdvent looks at how festive poinsettia plants can be used as a colourful pH indicator 🌈

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It's December, which means it's #ChemistryAdvent time again! Follow along in this thread every day, kicking off with the molecules behind the piney scent of Christmas trees 🎄

This weekend I will be working more on the "United Federation of Instances"

First thing I want to do is go through all the issues in the repo and try to comment or add my opinion on them.

Feel free to get in on the conversation here, its open to everyone.

Next I will work more on finishing the full bylaws, and try to incorperate any new perspectives from the discussions in the issues (eventually we can vote on the final wording).

Anyone interested in seeing the progress on that (the first draft isnt done) you can check that out here:

Of course you can see the original proposal document (which is the easier read and sumarizes the bylaws) here:

If anyone wants to contribute just join the first link I mentioned and feel free to offer merge requests. Also if anyone wants to help work on things like a website for us please speak up.

As always if you want to get into the conversation there are two ways other than the gitlab.

The first is fediverse groups: @ufoi

The other is our matrix chat room:

Hope to see you all there.

So we went with a study that looks at the influence of experimenter sex on mouse behavior and their response to ketamine:
It seems mice show aversion towards males & exposure to male scents activates the corticotropin-releasing factor neurons in the entorhinal cortex. Plus, this pathway must be activated before ketamine administration, or ketamine won’t produce its antidepressant effects.

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Day 2 of asks us to talk about a discovery that impressed us this year.
Originally we were planning on talking about this paper which introduces a new way of delivering targeted epidural electrical stimulation for restoring trunk and leg motor functions after spinal cord injuries:
But our uni doesn’t subscribe to Nature Medicine and we couldn’t find it anywhere on the internet, so we had to settle for something else.

So here's the thing. You can only violate people's legal rights and your own word so far before they lawyer up and come after you.

I really do hope Musk changes his mind and does the right thing - the employees deserve that. But it'll be fun as hell if he doesn't.

Hello again, all you wuffly people, and happy #ThrowbackThursday

I hope your week has been going great. The weekend is so close now!

Since it's December now, my throwback picture was Dad's attempt last year to get a photo for the family Christmas card. You can tell from my face I'm not amused.

Have a great rest-of-your-day, frens. See you tomorrow ❤️ 🐶

#Dog #Dogs #DogsOfMastodon #BorderCollie #AustralianKelpie #Christmas #SantaPaws #DadWillPayForThis

Is there no end to these speculative studies?

"Brains of post-pandemic teens show signs of faster ageing, study finds"

'Ageing' here could as easily be read as 'maturing', perhaps what you'd expect in teens who live through societal challenges.

Brain imaging studies are often ambiguous, underpowered & peculiar to a specific time/place. This study, focusing on a target group of 64 Californian 16-year-olds, tells us very little of substance.

#Psychology #covid #brain

Should've probably shared this earlier, but I pretty much forgot. In December, we'll do a little challenge. We've come up with 20 science-related prompts and every day we will share our neuroscience take on one of them. If you'd like to join in as well and share cool stuff from your field, here are the prompts:

Don't forget to use the hashtag .

The first prompt is "A scientist you admire". We picked a true legend in neuroscience: Brenda Milner. Here's our take on it:

Looking forward to learning about awesome scientists from other fields!

Write something quickly
and get it online.
It doesn’t have to be special
you don’t have the time.
Just find a topic,
and just get it down.
Don’t fuss with the spelling,
it will never be found.
Maybe 10 people see it.
6 people savour.
4 people like.
1 boosts to show favour. 😍
Ok that’s it,
good enough for now.
Just copy and post it.
before you run out of powe…..

#Poem #poetry #Oldphones

If you enjoyed this offering,
others might too.
So please boost and follow,
but it’s up to you.

The Canine Brains Project has finally joined Mastodon! Here's our #introduction! 🐶 🧠 🎓

We are scientists from Harvard's Hecht Lab who are studying dog #neuroscience and #behavior. We are interested in how #genes, #neuroanatomy, #dogtraining, and lifetime experiences shape dogs' minds. We also study how dog brains and behaviors #evolve.

#dog #dogsofmastodon #evolution #EvolutionaryBiology #evolutionaryneuroscience #animalbehavior #ethology #MRI #neuroimaging #workingdogs

So this paper came out last month claiming to find evidence of #quantum entanglement in the BRAIN! Of course it' s making a big splash in the popular press. My gut reaction is to be highly skeptical. Does anyone know enough #MRI #physics to judge what's going on?


As I replied on Twitter (wickedly since I believe that we all should leave it) after a postdoc with Larry Weiskrantz I applied for jobs at Sheffield University and Sussex University in the UK and failed to get them. Then I got a permanent job at Oxford.

3,013 neurons, half a million synapses: the complete #connectome of the whole #Drosophila larval brain!

Winding, Pedigo et al. 2022. "The connectome of an insect brain"

We’ve mapped and analysed its circuit architecture, from sensory neurons to brain output neurons, as reconstructed from volume electron microscopy, and here is what we found. 1/

#neuroscience #connectomics #vEM #volumeEM

Remember to say No to 90% of the things someone asks you to do. To things where "help is needed". To things that you know you could rock.

You have neither the time nor the energy to do it all.

Is what I said to myself today, too.

Just published

A universal influenza mRNA vaccine effective against all 20 lineages of influenza A and B, protective in experimental models

If you're like me, then you were really happy to learn about Mastodon's enthusiastic support for image descriptions, and you were really eager to join in.

Then you went to actually write something and realized you have no idea how to present visual information in a way that is helpful/enjoyable to those who are #VisuallyImpaired or #Blind.

I found this guide really informative:

Of course, I'd also love to hear any additional tips y'all might have!


New! Now published in the latest issue of 'Brain' >> our article on why it is dangerously wrong to attribute postural tachyardia syndrome (POTS) to psychogenic processes.

Or in plain language:

This symptom of #MECFS and #LongCovid reflects central neurological is not "all in the mind".

#Psychology #medicine #pwME

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