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RT @KapiteinLukas
New preprint for the lab! We introduce GelMap, a method enabling intrinsic calibration and deformation mapping for expansion microscopy.
@DamstraHugo @JosiahPassmore @fjmeye

biorxiv.org/content/10.1101/20

Wonderful article about Michael Sars, his son and their famous discoveries, for the very first time, the describtion of the different stages of a jellyfish life cycle. And ctenophores included as well 🤩.

uib.no/en/sarscentre/159096/se

RT @JohanD13016359@twitter.com

Postdoc position in 3D imaging available in the team for 2 years to participate to the AtlaSymbio project funded by @MooreFound@twitter.com in close collab. with @SchwabYannick@twitter.com @RCC_algae@twitter.com and the TREC expedition. Please RT. Application and info on photosymbiosis.com/job-offer/

🐦🔗: twitter.com/JohanD13016359/sta

Beautiful illustration from postdoc Margot Riggi (@MargotRiggi on Twitter) depicting a cross-section of Asgard archaea with actin filaments within. Based on recently published work from the Pilhofer Lab: nature.com/articles/s41586-022

RT @PilhoferLab
Asgard archaea reignited discussions about the tree of life 🦠 But do they have eukaryotic features? YES!! 🤩 Check out our new paper @Nature by @F_Wollweber and @xujw_thu, in an exciting collaboration with the Schleper lab @Archaea_Vienna. nature.com/articles/s41586-022
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Our “year in review” editorial to close 2022 👇🏼👇🏼

See our editor picks of the year (there were many more!) & read about life at the journal in 2022

Huge thanks to all of our Academic Editors, authors and reviewers for supporting @PLOSBiology 🙏🏻🙏🏻

Happy Xmas everyone! Nonia out
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RT @PLOSBiology
As we near the end of 2022, we look back at some of the changes that have taken place at #PLOSBiology, highlight some of our editors’ favo…
twitter.com/PLOSBiology/status

Synapses continue to be the most mysterious and perhaps most unknown component of nervous systems. First, synapses were found to pass viral-like capsids to postsynaptic neurons [1]. Now, synapses are found to mediate the transfer of vesicles with proteins in them (exosomes) among neurons [2], with selectivity e.g., to excitatory but not inhibitory neurons.

[1] Pastuzyn et al. 2018 on the Arc gene sciencedirect.com/science/arti

[2] Schiapparelli et al. 2022 cell.com/cell-reports/fulltext

RT @Centriolelab
Delighted to present our latest work in collab with @Dey_Gautam and @LoewithLab labs (Kudos to @KHinterndorfer @MarineLaporte8 @F_Mikus). We applied U-ExM to S. cerevisiae and S. pombe and combined HPF with U-ExM for optimal organelle preservation
journals.biologists.com/jcs/ar

Let's get #SciArt flowing into Mastodon!
What are some of your #SciArt (science-themed art) works you want to highlight? I will boost.

After trying many different media over the years (including drawing, embroidery etc) I found love in pottery. Now I make pottery pieces that highlight underappreciated organisms. Here are some examples of #worms, #jellyfish, #instects, #spiders etc. These are all boxes with lids!

'Why some animals can regenerate while many others cannot remains a fascinating question. Even amongst planarian flatworms, well-known for their ability to regenerate complete animals from small body fragments, species exist that have restricted regeneration abilities or are entirely regeneration incompetent. Towards the goal of probing the evolutionary dynamics of regeneration, we have assembled a diverse live collection of planarian species from around the world.'

biorxiv.org/content/10.1101/20

Probing the evolutionary dynamics of whole-body regeneration within planarian flatworms

Why some animals can regenerate while many others cannot remains a fascinating question. Even amongst planarian flatworms, well-known for their ability to regenerate complete animals from small body fragments, species exist that have restricted regeneration abilities or are entirely regeneration incompetent. Towards the goal of probing the evolutionary dynamics of regeneration, we have assembled a diverse live collection of planarian species from around the world. The combined quantification of species-specific head regeneration abilities and comprehensive transcriptome-based phylogeny reconstructions reveals multiple independent transitions between robust whole-body regeneration and restricted regeneration in the freshwater species. Our demonstration that the RNAi-mediated inhibition of canonical Wnt signalling can nevertheless bypass all experimentally tractable head regeneration defects in the current collection indicates that the pathway may represent a hot spot in the evolution of planarian regeneration defects. Combined with our finding that Wnt signalling has multiple roles in the reproductive system of the model species S. mediterranea, this raises the possibility of a trade-off between egg-laying and asexual reproduction by fission/regeneration as a driver of regenerative trait evolution. Although initial quantitative comparisons of Wnt signalling levels, reproductive investment, and regenerative abilities across the collection confirm some of the model's predictions, they also highlight the diversification of molecular mechanisms amongst the divergent planarian lineages. Overall, our study establishes a framework for the mechanistic evolution of regenerative abilities and planarians as model taxon for comparative regeneration research. ### Competing Interest Statement The authors have declared no competing interest.

www.biorxiv.org

The revised version of our paper on the desmosomal of the larva is now out
elifesciences.org/articles/712
by Sanja Jasek et al.

Applications for the Embryology Course at the MBL Woods Hole are open! If you or someone you know wants to learn Developmental Biology from very cool people and get your hands on over 100 species (from sponges, jellyfishes, small worms, big worms, through fishes, frogs, chicken, or mice), apply! Scholarships are always available, lodging and food included. If you have any Q about it, reach out to me #DevBio #DevBiol #Embryology #Microscopy #CellBio #BlackInBio #FirstGen

mbl.edu/education/advanced-res

RT @Centriolelab
Interested in learning Expansion Microscopy U-ExM, Cryo-ExM, iU-ExM, and Pan-ExM? The workshop we are organizing with @Dey_Gautam and @Group_Banterle at EMBL Imaging Centre is now open twitter.com/EMBLEvents/status/

Our review with Stefan Gründer and Audrey Ortega Ramírez is out:

"Neuropeptides and DEG/ENaC ion channels: a relationship from mammals to cnidarians"

where we conclude based on structural comparisons and the of systems that the interaction of DEG/ENaC channels with neuropeptides has diverse structural bases and many origins.

doi.org/10.1113/JP282309

Neuro-evo conference at HHMI Janelia on May 15-18, 2023. Join us for the third edition!

Application deadline: Jan 27 (11:59 p.m. EST) 2023.

Apply here: janelia.org/you-janelia/confer

"Historically, with the study of the most convenient animal models —from the giant axon of the squid and the lobster's stomatogastric circuits to Aplysia's synapses and C. elegans' circuits — neuroscientists revealed some of the operating principles of the nervous system, which were then found to apply broadly across phyla. The third instalment of this meeting will once again bring together neuroscientists working on a broad diversity of animal models in an effort to compare circuits across phyla as a means to crack their function."

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