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This past weekend we released setuptools 42.0, which has some big changes:
1. easy_install officially deprecated, with some workflows falling back to pip if installed!
2. Removed upload and register commands.
3. Support plugin keywords in setup.cfg
The easy_install change will probably break all kinds of weird edge cases, but in the end it's definitely for the best.
The only thing that bothers me about it is that it's very hard to declare our "opportunistic dependency" on pip.