@CenturyAvocado I guess success in that depends on how much it's used and by who and with what.
For internal stuff, yes. Public web server, without front end caching, or mail server without a friendly backup mx with IPv4, probably not.
@CenturyAvocado @zymurgic servers are generally okay. You will want some kind of NAT64 for outgoing connections, and IPv4 for incoming reverse proxy (eg a CDN). The default config, like you found out, often isn't correct.
Home/personal computers are a lot worse, as there are things that just don't work, eg Steam.