Whole adult fly brain connectome for FAFB (female adult fly brain) – last year in preprint form, today as an immersive feature in Nature.

140,000 neurons, over 50 million synapses – organised into over 8,000 cell types. (VNC not included.)

nature.com/immersive/d42859-02

The whole connectome: Dorkenwald et al. 2024 (Seung, Murthy) nature.com/articles/s41586-024

Cell types: Schlegel et al. 2024 (Jefferis) nature.com/articles/s41586-024 by @uni_matrix

Network statistics: Lin et al. 2024 (Murthy) nature.com/articles/s41586-024

Visual system: Garner et al. 2024 (Wernet, Kim) nature.com/articles/s41586-024 and Matsliah et al. (Murthy, Seung) nature.com/articles/s41586-024

Seung also put out a solo paper on predicting visual function from the connectome: nature.com/articles/s41586-024

Control of halting in walking: Sapkal et al. 2024 (Bidaye) nature.com/articles/s41586-024

FAFB imaged by @davi 's group back in 2018: cell.com/cell/fulltext/S0092-8

#neuroscience #Drosophila #connectomics #FAFB

@albertcardona @uni_matrix @davi

Is there a table format of different features, formats, usages, integrations, etc. Or intro readings for prime overview of such may connectomics software tools?

flywire.ai/apps
braincircuits.io/resources

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@teixi @albertcardona @davi

The closest thing I can think of is a paper from 2022: "A Survey of Visualization and Analysis in High-Resolution Connectomics" (PDF linked below) - you can browse an interactive version of it at connectomics-vis-survey.github

The technological landscape is pretty complex - although it feels like we are starting to see some convergence when it comes to data backends.

Link to paper PDF: vcg.seas.harvard.edu/publicati

@uni_matrix @albertcardona @davi

Oh many thanks P! for sharing this paper & repo, it is even more than I could expecting for!

Authors really did teaching explains for understanding the inners of all the bio structures together with all the tech involved in data acquisition, processing, classification, computing, visualization & exploration.

Also all paper tables & figures so crucial to learn, understand, & think about current #connectomics #omics tech tools!

@uni_matrix @davi

ps: also includes nice paragraph on #TrakEM2 by @albertcardona et al. w/ remark on alignments errors auto correction.

As for #catmaid collaborative annotation & neuronal structures skeletons approach!

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