#TOPMed
These are public posts tagged with #TOPMed. You can interact with them if you have an account anywhere in the fediverse.
Happy to report our review in Current Atherosclerosis Reports!
#Telomere Length: Implications for Atherogenesis
by me & my supervisor Dr. J. Geoffrey Pickering
TL as a biomarker & causal factor for ASCVD
Evidence from seminal studies, incld #UKBiobank #TOPMed
https://link.springer.com/article/10.1007/s11883-023-01082-6
https://www.nature.com/articles/s41588-022-01225-6 "Powerful, scalable and resource-efficient meta-analysis of #rareVariant associations in large whole genome sequencing studies" #wgs #genetics #genomics #bioinformatics #MetaSTAAR performs rare variant meta-analysis at scale and produces results comparable to using pooled data. We further demonstrate that MetaSTAAR is scalable to biobank-scale cohorts through meta-analysis of #TOPMed WGS data and #UKBiobank WES data of ~200,000 samples.