#TissueEngineering

These are public posts tagged with #TissueEngineering. You can interact with them if you have an account anywhere in the fediverse.

Furqan Shah

🔬🦴🧪 Magnesium implant degradation provides immunomodulatory and proangiogenic effects and attenuates peri-implant fibrosis in soft tissues" 🔎

#biomaterials #tissueengineering #regenerativemedicine #biology #implants #inflammation #immunomodulation #fibrosis #medicine #healthcare #engineering #magnesium #science

Implants made of magnesium (Mg) are increasingly employed in patients to achieve osteosynthesis while degrading in situ. Since Mg implants and Mg2+ have been suggested to possess anti-inflammatory properties, the clinically observed soft tissue inflammation around Mg implants is enigmatic. Here, using a rat soft tissue model and a 1–28 d observation period, we determined the temporo-spatial cell distribution and behavior in relation to sequential changes of pure Mg implant surface properties and Mg2+ release. Compared to nondegradable titanium (Ti) implants, Mg degradation exacerbated initial inflammation. Release of Mg degradation products at the tissue-implant interface, culminating at 3 d, actively initiated chemotaxis and upregulated mRNA and protein immunomodulatory markers, particularly inducible nitric oxide synthase and toll-like receptor-4 up to 6 d, yet without a cytotoxic effect. Increased vascularization was demonstrated morphologically, preceded by high expression of vascular endothelial growth factor. The transition to appropriate tissue repair coincided with implant surface enrichment of Ca and P and reduced peri-implant Mg2+ concentration. Mg implants revealed a thinner fibrous encapsulation compared with Ti. The detailed understanding of the relationship between Mg material properties and the spatial and time-resolved cellular processes provides a basis for the interpretation of clinical observations and future tailoring of Mg implants.
Aug 30, 2024, 08:09 · · 1 · 0
Scientific European

3D Bioprinting Assembles Functional Human Brain Tissue for The First Time  
Scientists have developed a 3D bioprinting platform that assembles functional human neural tissues............
#3Dbioprinting #Bioprinting #brain #neurons #TissueEngineering
Umesh Prasad

scientificeuropean.co.uk/techn

Feb 07, 2024, 13:43 · · 0 · 0
Dr. Marie McNeely

This week's new PBtS podcast episode features Dr. Claire Higgins! She discussed her research on tissue engineering and regenerative medicine, her passion for pottery, memorable trips to Kyoto, exciting recent research successes, and more! peoplebehindthescience.com/dr-

#podcast #podcasts #scicomm #biology #hair #skin #science #STEM #regenerativemedicine #tissueengineering

On the right side of the image, our podcast cover art is displayed. The text reads "People Behind the Science with Dr. Marie McNeely". On the left side, there is a headshot photo of Dr. Claire Higgins. She has long blonde hair, she is wearing a dark green top, and she is standing in front of a tan marbled background. She is looking at the camera and smiling.
Jan 08, 2024, 16:09 · · 1 · 1
Gonzalo

Just Published!

"Recellularization of Acellular Xeno Kidney Scaffold: An In Vivo Method to Generate Bioartificial Kidney"

link.springer.com/chapter/10.1

#RegenerativeMedicine #TissueEngineering

Aug 24, 2023, 12:16 · · 0 · 0
University of Limerick

5 advances in tissue engineering you need to know about

Tissue engineering has potential to provide personalised healthcare, grow tissues & organs in the lab & reduce organ donor waiting lists, as UL's Dr Aleksandra Serafin explains:
rte.ie/brainstorm/2023/0414/13

#StudyatUL #Healthcare #Engineering #TissueEngineering #Research #HigherEducationResearch #Learning #Education #University

A photograph of a pipette filling glass beakers with a clear liquid in a research lab. The shot is taken from above showing only the tip of the pipette and the beakers below, which are lit with blue and pink lights
Apr 17, 2023, 10:47 · · 0 · 0
Alan Kotok

Bio-Electric Regeneration Company Adds $8M in Seed Funds

A start-up enterprise, spun-off from Tufts University labs, creating bio-electrical #treatments for #regenerating #limbs and #tissue, is raising $8 million in new #seed funds. sciencebusiness.technewslit.co

#News #Science #Business #StartUp #Biotechnology #BioElectric #RegenerativeMedicine #TissueEngineering #ComputationalBiology #Finance #VentureCapital #SeedFunds

African clawed frog
Feb 16, 2023, 19:04 · · 1 · 0
halama_immuno

Building blocks made from living cells...an emergent therapeutic strategy. We still have to find the "treasure chest" of suitable targets and the right order of intervention... #bioengineering #cellulartherapies #tissueengineering #organoids #explantmodels #immunology
scim.ag/Xu

Dec 23, 2022, 19:42 · · 1 · 1
Christian Tidona

Did you know that during #embryo development, migrating #monocytes deposit tracks of pro-angiogenic #migrasomes guiding the formation of blood vessels?

In this interesting manuscript published in Nature Cell Biology, researchers at Tsinghua University in Beijing studied this phenomenon in the chorioallantoic membrane of chick embryos: nature.com/articles/s41556-022

This could have implications in organotypic #tissueengineering and provide new ways how to inhibit #angiogenesis in solid #tumors.

Dec 22, 2022, 09:21 · · 0 · 0

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