IL-11 as a therapeutic target for lung #Fibrosis #Emphysema in #MarfanSyndrome
In Marfan🐭🫁, IL11-GFP reporter is active in #EndothelialCell #SmoothMuscleCell Fibroblast but not alveolar epithelia
Dr. Stuart A Cook & Wei Wen Lim lab ATVB 2023
https://www.ahajournals.org/doi/10.1161/ATVBAHA.122.318802
Also don't miss the story on IL-11 as mediator of Mafan #Aortopathy from Circ Res 2022
https://www.ahajournals.org/doi/10.1161/CIRCRESAHA.121.320381